Predictability of serum vancomycin concentrations using the kinetic estimated glomerular filtration rate formula for...

To evaluate the predictability of serum vancomycin concentrations of critically ill patients using the new kinetic estimated glomerular filtration rate (KeGFR) and other three established eGFR formulae.

We calculated serum vancomycin concentrations using software provided by the manufacturer of vancomycin.

Data were collected from 122 hospitalized adults. The mean error and mean absolute error of KeGFR were 0.81 µg/mL and 4.46 µg/mL, respectively. The root mean squared prediction error of KeGFR was the highest (6.67 µg/mL) among the four formulae.

The predictability of KeGFR formula did not show good accuracy in critically ill patients.
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