Related Experiment Video
Updated: Feb 5, 2026

Micromanipulation of Circulating Tumor Cells for Downstream Molecular Analysis and Metastatic Potential Assessment
Published on: May 14, 2019
Circulant embedding with QMC: analysis for elliptic PDE with lognormal coefficients
Ivan G Graham1, Frances Y Kuo2, Dirk Nuyens3
11Department of Mathematical Sciences, University of Bath, Bath, BA2 7AY UK.
This study provides a convergence analysis for a computational method combining quasi-Monte Carlo and circulant embedding for solving partial differential equations with random coefficients. The method shows potential for efficient computation, even with many random variables.
Area of Science:
- Computational mathematics
- Numerical analysis
- Scientific computing
Background:
- A previous study introduced a practical method for computing expected values of functionals for elliptic partial differential equations with random coefficients.
- This method combined quasi-Monte Carlo (QMC) and circulant embedding for sampling random fields, proving effective for high-dimensional stochastic problems like fluid flow in heterogeneous media.
- However, the prior work lacked a rigorous convergence theory.
Purpose of the Study:
- To provide a convergence analysis for the previously proposed computational method.
- To investigate the method's performance when using a specific type of QMC: randomly shifted lattice rules.
- To establish convergence rates that may be independent of the number of stochastic variables.
Main Methods:
- The study employs a convergence analysis framework for the combined QMC and circulant embedding method.
- The analysis focuses on randomly shifted lattice rules as the quasi-Monte Carlo component.
- It incorporates error analysis for the finite element method, accommodating locally refined meshes.
Main Results:
- A convergence result is established for the method when using randomly shifted lattice rules.
- The convergence rate is shown to depend on the eigenvalues of the underlying nested block circulant matrix.
- Under specific assumptions, the convergence can be independent of the number of stochastic variables, and the QMC analysis extends to general covariance matrix factorizations.
Conclusions:
- The paper successfully provides a theoretical convergence analysis for the computational method.
- The findings support the method's efficiency and applicability to complex problems, including those with high stochastic dimensions.
- Numerical validation on 2D and 3D domains, including those with singularities, demonstrates the method's practical utility.
Related Concept Videos
Coefficient of Variation
The coefficient of variation is a practical statistical tool in finance. It allows investors to assess the volatility or...
Coefficient of Correlation
If you suspect a linear relationship between x and y, then r can measure how strong the linear relationship is.
What the VALUE of r tells us:
The value of r is always between –1 and +1: –1 ≤ r ≤ 1.
The size of the correlation r indicates the...
Confidence Coefficient
Thermodynamics: Activity Coefficient
The activity coefficient is a measure of the deviation from ideal behavior. When the ionic strength of the solution is minimal, the activity coefficient of an ionic species is close to unity, making...
Factors Affecting Activity Coefficient
The activity coefficient value for an ion is close to one when the solution has almost zero ionic strength, i.e., when the solution shows close to ideal behavior. As the ionic strength of the solution increases from 0 to 0.1 mol/L, a...
Kendall's Coefficient of Concordance

