Related Experiment Video
Updated: Feb 5, 2026
Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid
Published on: June 17, 2025
Ocular cicatricial pemphigoid
Kaidi Wang1, Gerami Seitzman, John A Gonzales
1Francis I. Proctor Foundation, Department of Ophthalmology, University of California, San Francisco, California, USA.
Purpose Of Review:
This review offers recommendations for monitoring disease status in ocular cicatricial pemphigoid as well therapeutic options including local and systemic therapies.
Recent Findings:
A negative biopsy on direct immunofluorescence does not preclude a diagnosis of OCP. If a patient's cicatrization is active and/or progressive, systemic immunosuppression should be commenced.
Summary:
OCP is a chronic systemic autoimmune disease that requires systemic immunosuppression.
