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Transcatheter aortic valve replacement: The year in review 2017
Kamia Thakur1, Tamim M Nazif2, Omar K Khalique2
1Department of Internal Medicine, Geisinger Medical Center, Danville, Pennsylvania.
Transcatheter aortic valve replacement (TAVR) advanced in 2017, particularly for intermediate-risk patients, with new trials on cerebral protection and antiplatelet therapy. Newer valve systems also showed promising efficacy and safety profiles.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- Transcatheter aortic valve replacement (TAVR) has become a key treatment for aortic stenosis.
- Annual reviews track advancements in TAVR procedures and technologies.
- The 2017 landscape saw significant developments impacting patient selection and management.
Purpose of the Study:
- To summarize major transcatheter aortic valve replacement (TAVR) studies published in 2017.
- To highlight key findings from pivotal trials and research in TAVR.
- To provide an overview of emerging trends and evidence in TAVR.
Main Methods:
- Review of major randomized controlled trials and observational studies published in 2017.
- Analysis of research focusing on intermediate-risk patients, cerebral protection, and antiplatelet strategies.
- Evaluation of data on newer generation TAVR valve systems.
Main Results:
- The SURTAVI trial solidified TAVR's role in intermediate-risk patients.
- Studies investigated the efficacy and safety of cerebral protection devices during TAVR.
- Research compared single versus dual antiplatelet therapy post-TAVR.
- Newer TAVR valve generations demonstrated continued improvements in performance.
Conclusions:
- Transcatheter aortic valve replacement (TAVR) demonstrated significant progress in 2017, expanding its clinical utility.
- Cerebral protection and optimized antiplatelet regimens are key areas of ongoing research.
- Advancements in valve technology continue to enhance TAVR safety and effectiveness.
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