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Updated: Feb 5, 2026

Analysis of Gene Expression Changes in the Rat Hippocampus After Deep Brain Stimulation of the Anterior Thalamic Nucleus
Published on: March 8, 2015
Comparative mechanical analysis of deep brain stimulation electrodes
H H Draz1, S R I Gabran2, Mohamed Basha3
1Department of Microelectronics, Electronics Research Institute, El Tahrir st, El Dokki, 12622, Giza, Egypt.
Abstract:
The new field of neuro-prosthetics focuses on the design and implementation of neural prostheses to restore some of the lost neural functions. The electrode-tissue contacts remain one of the major obstacles of neural prostheses microstructure. Recently, Microelectrode fabrication techniques have been developed to have a long-term and stable interface with the brain. In this paper, a comparative analysis of finite element models (FEM) for several electrode layouts is conducted. FEM involves parametric and sensitivity analysis to show the effects of the different design parameters on the electrode mechanical performance. These parameters include electrode dimensions, geometry, and materials. The electrodes mechanical performance is evaluated with various analysis techniques including: linear buckling analysis, stationary analysis with axial and shear loading, and failure analysis for brittle and ductile materials. Finally, a novel figure of merit (FOM) is presented and dedicated to the various electrodes prototypes. The proposed designs take into account mechanical performance, fabrication cost, and cross sectional area of the electrode. The FOM provides important design insights to help the electrodes designers to select the best electrode design parameters that meet their design constraints.
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