Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inflammation01:38

Inflammation

62.1K
Overview
62.1K
Cancer02:18

Cancer

54.3K
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
54.3K
What is Cancer?02:12

What is Cancer?

14.4K
Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of...
14.4K
Cancer Prevention02:59

Cancer Prevention

8.1K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
8.1K
Cancer Vaccines01:30

Cancer Vaccines

1.1K
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
1.1K
Skin Cancer01:30

Skin Cancer

5.9K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Robotic surgery: The beginning and the journey so far.

The National medical journal of India·2026
Same author

New CPT codes for prostate biopsy improve alignment of reimbursement with evidence-based practice.

Urologic oncology·2026
Same author

Deep-learning computer-aided detection and classification of prostate lesions on biparametric MRI: comparison with expert readers.

Insights into imaging·2026
Same author

Intersection of phenotypic plasticity and anoikis enhances therapeutic vulnerability in prostate cancer.

Endocrinology·2026
Same author

Role of Pelvic Lymph Node Dissection for Clinically Localized Prostate Cancer: Should It be Done?

The Urologic clinics of North America·2026
Same author

Nerve-Sparing in High-Risk Prostate Cancer: Advantages and Pitfalls of Current Strategies and Technologies.

Cancers·2026
Same journal

Peptidomics in the Spotlight: Advanced Sample Treatment Techniques and Analytical Insights.

Advances in experimental medicine and biology·2026
Same journal

Methods for the Investigation of Protein-Ligands Interactions.

Advances in experimental medicine and biology·2026
Same journal

Sample Preparation Strategies for Microbial Cell Surface Proteomics: Integrating Shaving and Shotgun Approaches.

Advances in experimental medicine and biology·2026
Same journal

Proteomic Sample Preparation for the Petroleum Industry: A Biocorrosion Case Study.

Advances in experimental medicine and biology·2026
Same journal

Proteomic and Functional Comparison of Extracellular Vesicles from Wild-Type and Lyn-Deficient Stromal Cells.

Advances in experimental medicine and biology·2026
Same journal

Proteomic Analysis of Histone Sequence Variants and Post-translationally Modified Forms.

Advances in experimental medicine and biology·2026
See all related articles

Related Experiment Video

Updated: Feb 5, 2026

Isolation of Cancer Stem Cells From Human Prostate Cancer Samples
07:16

Isolation of Cancer Stem Cells From Human Prostate Cancer Samples

Published on: March 14, 2014

14.6K

Inflammation and Prostate Cancer.

Ashutosh K Tewari1, Jennifer A Stockert2, Shalini S Yadav2

  • 1Department of Urology, Icahn School of Medicine at Mount Sinai, New York, USA. ash.tewari@mountsinai.org.

Advances in Experimental Medicine and Biology
|September 20, 2018
PubMed
Summary
This summary is machine-generated.

Chronic inflammation is linked to 20% of cancers and plays a key role in prostate cancer development and progression. Understanding inflammation

Keywords:
Adaptive immune systemChemokinesCytokinesInflammationInnate immune systemLymphocytesMacrophagesOxidative stressProstate cancer

More Related Videos

An Orthotopic Murine Model of Human Prostate Cancer Metastasis
06:48

An Orthotopic Murine Model of Human Prostate Cancer Metastasis

Published on: September 18, 2013

35.9K
miRNA Expression Analyses in Prostate Cancer Clinical Tissues
11:29

miRNA Expression Analyses in Prostate Cancer Clinical Tissues

Published on: September 8, 2015

11.2K

Related Experiment Videos

Last Updated: Feb 5, 2026

Isolation of Cancer Stem Cells From Human Prostate Cancer Samples
07:16

Isolation of Cancer Stem Cells From Human Prostate Cancer Samples

Published on: March 14, 2014

14.6K
An Orthotopic Murine Model of Human Prostate Cancer Metastasis
06:48

An Orthotopic Murine Model of Human Prostate Cancer Metastasis

Published on: September 18, 2013

35.9K
miRNA Expression Analyses in Prostate Cancer Clinical Tissues
11:29

miRNA Expression Analyses in Prostate Cancer Clinical Tissues

Published on: September 8, 2015

11.2K

Area of Science:

  • Oncology
  • Immunology
  • Pathology

Background:

  • Chronic inflammation is a significant risk factor for cancer development, contributing to approximately 20% of all cancer cases.
  • Inflammation is increasingly recognized for its role in various stages of cancer, from initiation to metastasis.

Purpose of the Study:

  • To explore the critical role of inflammation in prostatic carcinogenesis and tumor progression.
  • To highlight the need for research into the etiology of prostatic inflammation and its associated signaling pathways.

Main Methods:

  • Review of genetic, epidemiological, and molecular pathological studies.
  • Analysis of the role of inflammatory mediators and signaling pathways in prostate cancer.

Main Results:

  • Inflammation is implicated in all stages of prostate cancer development, including initiation, promotion, malignant conversion, invasion, and metastasis.
  • Specific signaling pathways driven by inflammation are crucial for tumor growth and progression.

Conclusions:

  • Understanding the mechanisms linking inflammation to prostate cancer is essential for developing novel therapeutic strategies.
  • Targeting inflammatory mediators and utilizing immunotherapy hold promise for future prostate cancer treatments.