Open source capillary electrophoresis.

Area of Science:

• Analytical Chemistry
• Instrumentation
• Open Science

Background:

• Open source hardware and software are increasingly adopted in scientific research.
• Capillary electrophoresis (CE) is a flexible, cost-effective, and efficient separation technique.
• CE is well-suited for open source instrumental development.

Purpose of the Study:

• To provide an up-to-date overview of open source resources for constructing a capillary electrophoresis instrument.
• To consolidate accessible blueprints for key CE components.
• To encourage wider adoption and innovation in open source CE.

Main Methods:

• Literature and web-based review of open source hardware and software components for CE.
• Identification of resources for high voltage power supplies, detectors, data acquisition systems, and CE software.
• Compilation of accessible blueprints and design information.

Main Results:

• The review identifies and collates numerous open source resources for building a functional CE system.
• Accessible blueprints for major CE instrument parts are presented.
• Emphasis is placed on the availability of information in scientific literature and online.

Conclusions:

• This work is the first comprehensive review of open source CE instrumentation.
• The collected information facilitates the construction of a fully functional open source CE system.
• Dissemination of knowledge and fostering innovation in CE are key outcomes.