Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bootstrapping01:24

Bootstrapping

The term "bootstrap" originated in the 19th century as a metaphor for self-improvement or achieving something independently, without external assistance. This concept extends to statistical bootstrapping, a self-contained method for estimating population parameters through resampling, even though it can be computationally intensive. Developed by the American statistician Dr. Bradley Efron in 1979, bootstrapping provides a robust way to perform inference when the original sample size is small or...
Modified-Release Drug Delivery Systems: Rate-Programmed I01:22

Modified-Release Drug Delivery Systems: Rate-Programmed I

Rate-programmed drug delivery systems (DDS) are designed to release drugs at specific, controlled rates to maintain consistent therapeutic levels. These systems are categorized based on their release mechanisms, including dissolution-controlled DDS, diffusion-controlled DDS, and combined dissolution-diffusion-controlled DDS.In dissolution-controlled DDS, the release rate depends on the slow dissolution of the drug itself or the surrounding matrix. Drugs with inherently slow dissolution rates,...
Scale-Up Processes01:14

Scale-Up Processes

The scale-up of microbial fermentation processes is essential in industrial biotechnology, allowing the transition from laboratory-scale experiments to commercial-scale production while aiming to maintain product yield and quality. This process requires meticulous adjustment of equipment design, process parameters, and contamination control strategies to accommodate increasing culture volumes.At the laboratory scale, cultures are typically maintained in 1 to 10-liter glass or autoclavable...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same authorSame journal

Technology Licensing & Commercialization Considerations for Clinical Scientists.

LES nouvelles. Licensing Executives Society (U.S.A.)·2026
Same authorSame journal

R2B Contracts: Complexities And Considerations When Contracting With Universities And Other Not-For-Profit Research Organisations.

LES nouvelles. Licensing Executives Society (U.S.A.)·2025
Same authorSame journal

An Early TTO For U.S. Federal Labs-The National Technical Information Service.

LES nouvelles. Licensing Executives Society (U.S.A.)·2023
Same author

The U.S. National Institutes of Health - Founding A National Biomedical "Innovation Ecosystem".

Journal of commercial biotechnology·2021
Same author

Dystrobrevin is required postsynaptically for homeostatic potentiation at the Drosophila NMJ.

Biochimica et biophysica acta. Molecular basis of disease·2019
Same author

A Guide to Time Lag and Time Lag Shortening Strategies in Oncology-Based Drug Development.

Journal of commercial biotechnology·2017
Same journal

Recognizing NIH's Role in Turning Discoveries into Cancer Treatments.

LES nouvelles. Licensing Executives Society (U.S.A.)·2026
Same journal

Technology Transfer Magic Sauce Ingredients - When and Where to Use Them.

LES nouvelles. Licensing Executives Society (U.S.A.)·2026
Same journal

Will Artificial Intelligence Shape The Future Of Technology Transfer? A Guide For Licensing Professionals.

LES nouvelles. Licensing Executives Society (U.S.A.)·2024
See all related articles

Related Experiment Video

Updated: May 31, 2026

Scalable Fluidic Injector Arrays for Viral Targeting of Intact 3-D Brain Circuits
13:36

Scalable Fluidic Injector Arrays for Viral Targeting of Intact 3-D Brain Circuits

Published on: January 21, 2010

Accelerating Federal Technology Transfer Through a Startup Challenge Licensing Mode.

Steven M Ferguson1, Rosemarie Truman2, Cody J Locke3

  • 1National Institutes of Health.

LES Nouvelles. Licensing Executives Society (U.S.A.)
|May 29, 2026
PubMed
Summary
This summary is machine-generated.

Taxpayer-funded research yields significant innovations, but commercialization remains low. Despite billions invested annually, less than 0.1% of federally funded inventions reach the market, leaving valuable discoveries dormant.

More Related Videos

Laser-induced Forward Transfer for Flip-chip Packaging of Single Dies
08:21

Laser-induced Forward Transfer for Flip-chip Packaging of Single Dies

Published on: March 20, 2015

Synthesizing Lipid Nanoparticles by Turbulent Flow in Confined Impinging Jet Mixers
08:10

Synthesizing Lipid Nanoparticles by Turbulent Flow in Confined Impinging Jet Mixers

Published on: August 23, 2024

Related Experiment Videos

Last Updated: May 31, 2026

Scalable Fluidic Injector Arrays for Viral Targeting of Intact 3-D Brain Circuits
13:36

Scalable Fluidic Injector Arrays for Viral Targeting of Intact 3-D Brain Circuits

Published on: January 21, 2010

Laser-induced Forward Transfer for Flip-chip Packaging of Single Dies
08:21

Laser-induced Forward Transfer for Flip-chip Packaging of Single Dies

Published on: March 20, 2015

Synthesizing Lipid Nanoparticles by Turbulent Flow in Confined Impinging Jet Mixers
08:10

Synthesizing Lipid Nanoparticles by Turbulent Flow in Confined Impinging Jet Mixers

Published on: August 23, 2024

Area of Science:

  • Biotechnology
  • Medical Devices
  • Public Health

Background:

  • Billions in taxpayer funding support U.S. research and development.
  • Federally funded inventions have historically led to life-changing technologies and companies.
  • The National Institutes of Health (NIH) has successfully commercialized some technologies, including FDA-approved drugs and vaccines.

Purpose of the Study:

  • To analyze the commercialization rates of federally funded inventions.
  • To identify barriers to the market translation of public research.
  • To understand the impact of public investment on innovation.

Main Methods:

  • Analysis of federal R&D investment data.
  • Review of commercialization pathways for federally developed technologies.
  • Examination of success and failure rates in technology transfer.

Main Results:

  • Federally funded research generates numerous inventions with transformative potential.
  • Fewer than 0.1% of federally funded inventions are successfully commercialized.
  • Significant taxpayer investment results in dormant innovations.

Conclusions:

  • Despite successful examples, the vast majority of federally funded inventions do not reach the market.
  • There is a substantial gap between public investment in innovation and its commercial realization.
  • Strategies are needed to improve the commercialization of taxpayer-supported research and development.