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Updated: Feb 5, 2026

Grafting of Beads into Developing Chicken Embryo Limbs to Identify Signal Transduction Pathways Affecting Gene Expression
Published on: January 17, 2016
[Restoration of damaged cortical pathways by neural grafting]
Nissrine Ballout1, Sophie Péron1, Afsaneh Gaillard1
1Laboratoire des neurosciences expérimentales et cliniques, Inserm U1084, université de Poitiers, 1, rue Georges Bonnet, 86073 Poitiers, France.
Abstract:
The motor cortex plays a central role in the control, planning, and execution of voluntary motor commands in mammals. The loss of cortical neurons is a common feature of many neuropathological conditions such as traumatic and ischemic lesions or several neurodegenerative diseases. Cell transplantation presents a promising therapeutic strategy to overcome the limited abilities of axonal regrowth and spontaneous regeneration of the adult central nervous system. In this review, we will present a historical review of brain transplantation and the current state of research in the field of cortical transplantation.
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