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Risk Assessment and Treatment Guide for Obstetric Thromboprophylaxis: Comprehensive Review of Current Guidelines
Allison A Eubanks1, Shad H Deering2, Lisa M Thiel3
1Department of Obstetrics and Gynecology, Walter Reed National Military Medical Center, Bethesda, Maryland.
American Journal of Perinatology
|September 20, 2018
Summary
This study simplifies venous thromboembolism (VTE) prophylaxis in pregnancy by creating a one-page risk assessment guide. It ensures pregnant patients receive accurate VTE risk assessment and treatment during and after pregnancy.
Area of Science:
- Obstetrics and Gynecology
- Hematology
- Clinical Guidelines
Background:
- Conflicting recommendations exist for venous thromboembolism (VTE) prophylaxis during pregnancy.
- A simplified, evidence-based approach is needed for VTE risk assessment and treatment in obstetric patients.
Purpose of the Study:
- To develop a concise, one-page guide for VTE risk assessment and prophylaxis in pregnancy.
- To synthesize current evidence-based recommendations for antepartum and postpartum VTE prevention.
Main Methods:
- Conducted a comprehensive literature search on PubMed and MEDLINE (1980-2017) for VTE prophylaxis in pregnancy.
- Selected 10 key articles and guidelines based on relevance and citation frequency.
- Utilized American College of Obstetrics and Gynecology guidelines as a base for screening and dosing.
Main Results:
- A single-page VTE risk assessment and treatment guide was created.
- Recommendations cited in at least three sources were included.
- Risk stratification used published absolute risk values and odds ratios for antepartum and postpartum periods.
Conclusions:
- The developed guide simplifies VTE prophylaxis for obstetric patients.
- Facilitates early and accurate identification of women requiring VTE prevention.
- Aims to improve maternal safety during and after pregnancy.
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