Related Experiment Video
Updated: Apr 14, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
Social Media and Supplements for Menopausal Symptoms: A Content Analysis
Allison A Eubanks1, Katerina Shvartsman2
1Department of Reproductive Endocrinology and Infertility, Walter Reed National Military Medical Center, Bethesda, Maryland, USA.
Objective:
To evaluate the role of social media in promoting menopause-related supplements and assess the evidence supporting their efficacy and safety.
Design:
Observational content analysis.
Setting:
Public Instagram posts using menopause-related hashtags.
Population Or Sample:
A dataset of 1000 Instagram posts retrieved using 10 menopause-related hashtags.
Methods:
Using a newly created Instagram account, we reviewed the top 100 posts from each of the 10 most popular menopause hashtags. Posts advertising branded oral supplements were categorized by poster type and message intent. The 20 most frequently promoted supplements were analyzed for active ingredients, monthly cost, and evidence-based efficacy. Data was collected in June 2024.
Main Outcome Measures:
Poster background, content category, ingredient profile, product cost, and safety and efficacy data.
Results:
Of 1000 Instagram posts reviewed, 661 (66.1%) promoted branded menopause supplements. Only 18.3% were authored by credentialed clinicians, while most were posted by businesses (30.4%) or non-clinical individuals (51.3%). Among the top 20 advertised supplements, common ingredients such as black cohosh and chaste tree extract showed inconsistent evidence. Nearly half (45%) contained proprietary blends, limiting transparency. The average monthly cost was $43.49 (USD).
Conclusions:
Menopause supplement marketing on Instagram is dominated by non-clinicians and often lacks supporting evidence or regulatory oversight. Clinicians should be aware of this online landscape and address supplement use during patient consultations.
More Related Videos
Related Concept Videos
Menopause
Hormonal Regulation
Hormonal Regulation
Hormonal Regulation of the Menstrual Cycle
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
Gonadal and Placental Hormones
In males, testosterone is the primary gonadal androgen. It plays a central role in the maturation of male reproductive organs — the penis and testes. Additionally, testosterone is instrumental in the development of secondary sexual characteristics — a deep voice as well as facial and pubic hair...
Secondary Messengers in Hormone Action
Many hormones bind to transmembrane G protein-coupled receptors that connect to regulatory G proteins. These G proteins can then activate enzymes such as adenylyl cyclase or phospholipase C. Adenylyl cyclase converts ATP to cAMP, activating...

