Related Experiment Video
Updated: Feb 5, 2026

Quantitative Assessment of Cortical Auditory-tactile Processing in Children with Disabilities
Published on: January 29, 2014
Migraine in children: presentation, disability and response to treatment
Shalonda K Slater1,2, Scott W Powers1,2, Hope L O'Brien3,2
1Division of Behavioral Medicine and Clinical Psychology.
Insights
Pediatric migraine treatments require further investigation. Recent studies indicate that some preventive medications may not be more effective than placebo for children experiencing migraines.
Area of Science:
- Pediatric Neurology
- Clinical Pharmacology
- Headache Medicine
Background:
- Migraine is a prevalent neurological condition in children, impacting their quality of life.
- Understanding the presentation, consequences, and treatment of pediatric migraine is crucial for effective management.
Purpose of the Study:
- To review current findings on pediatric migraine, including its presentation, consequences, and available medication treatments.
- To critically evaluate the efficacy of different treatment approaches for migraine in children.
Main Methods:
- Systematic review of recent investigations into pediatric migraine.
- Analysis of studies comparing pharmacological interventions with placebo.
- Examination of barriers in designing clinical trials for pediatric migraine.
Main Results:
- Advancements have been made in understanding pediatric migraine, but treatment effectiveness varies.
- Preventive medications were found not to be statistically more effective than placebo in a recent study.
- High placebo response rates and headache characteristics pose challenges for clinical trial design.
Conclusions:
- While some migraine treatments are effective in children, robust controlled studies on medication effectiveness are limited.
- Further research is necessary to elucidate treatment mechanisms and confirm the efficacy of medication interventions.
- Additional investigation is needed to optimize migraine headache care for pediatric populations.
Purpose Of Review:
The current review presents findings from investigations of migraine in children. The presentation of pediatric migraine, related consequences, and medication treatments are reviewed.
Recent Findings:
A number of advancements have been made in the study of the presentation, disability, and treatments for migraine in children. However, recent research suggests that not all approaches are equally effective in the treatment of migraine in children. Specifically, a recent study comparing pharmacological interventions found that preventive medications were not statistically more effective than placebo in children. Consistent findings showing clinically meaningful placebo response rates, shorter duration of headaches and other characteristic features (e.g. frontal, bilateral location) have been barriers to the design of randomized clinical trials in children and adolescents with migraine. Better understanding of treatment mechanisms for medication interventions is needed.
Summary:
Several migraine treatments have determined to be effective for use in children but few controlled studies have evaluated the effectiveness of medication treatments. Recent research suggests that preventive medications may not be more effective than placebo. Additional research is needed to evaluate the effectiveness of medication treatment in migraine headache care.
Related Concept Videos
Self-Presentation
Self-Presentation: Self-Monitoring and Self-Handicapping
Strategies of Self-Presentation I: Strategic Self-Presentation
Intellectual Disability
Learning Disabilities
Dyslexia
Dyslexia is a...
Processes of Self-Presentation

