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Usefulness of urinary parameters in advanced chronic kidney disease

Víctor Lorenzo Sellarés1

  • 1Hospital Universitario de Canarias, Santa Cruz de Tenerife, España.

Nefrologia
|September 22, 2018
PubMed

Insights

Monitoring urinary parameters like volume, urea nitrogen, and phosphorus is crucial for managing advanced chronic kidney disease (CKD). These provide insights into dietary habits and adherence to treatment recommendations.

Area of Science:

  • Nephrology
  • Clinical Nutrition
  • Diagnostic Biomarkers

Background:

  • Advanced chronic kidney disease (CKD) management requires careful monitoring of various physiological parameters.
  • Dietary habits significantly impact CKD progression and patient outcomes.
  • Urinary parameters offer valuable, non-invasive insights into a patient's metabolic status and adherence to nutritional recommendations.

Purpose of the Study:

  • To review the diagnostic utility of urinary parameters in advanced CKD.
  • To provide evidence-based recommendations for monitoring key urinary indicators.
  • To highlight the role of urinary analysis in assessing dietary intake and adherence in CKD patients.

Main Methods:

  • Review of existing literature on urinary parameters in CKD.
  • Analysis of established correlations between urinary output and dietary intake (fluids, sodium, protein, phosphorus).
  • Discussion of indirect methods for estimating acid load and potassium excretion.

Main Results:

  • Recommended urinary output of ≥2-3 L/day (excluding specific conditions).
  • Target urinary sodium excretion <120 mEq/day to monitor salt intake.
  • Urinary urea nitrogen (UUN) estimation of protein intake (48-72g/day).
  • Suggested urinary phosphorus (P) excretion limits based on GFR (<800mg/day for GFR <25ml/min, <600mg/day for GFR <15ml/min).

Conclusions:

  • Urinary parameters are sensitive and clinically useful tools in advanced CKD.
  • These parameters provide critical information on patient dietary habits.
  • Monitoring urinary biomarkers aids in assessing adherence to therapeutic recommendations and optimizing CKD management.

Keywords:
Advanced chronic kidney diseaseChronic kidney diseaseEnfermedad renal crónicaEnfermedad renal crónica avanzadaHidrataciónHydrationNutriciónNutritionParámetros urinariosUrinary parametersUrinary volumeVolumen urinario

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