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Updated: Feb 5, 2026

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Published on: December 6, 2016
Preventing Opioid-Induced Respiratory Depression in the Hospitalized Patient With Obstructive Sleep Apnea
Purpose:
To enhance the role of nursing interventions in the management of perioperative opioid-induced respiratory depression (OIRD) in patients with obstructive sleep apnea (OSA).
Design:
Narrative review of the literature.
Methods:
Literature reviewed with emphasis on recommendations by professional and accrediting organizations.
Findings:
Postsurgical OIRD increases hospital stay (55%), cost of care (47%), 30-day readmission (36%), and inpatient mortality (3.4 fold). OSA increases the risk of OIRD and may result in legal claims averaging $2.5 million per legal claim.
Conclusions:
Nursing interventions are essential to improving outcome and reduce cost in the management of postsurgical OIRD in OSA patients.
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