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Comparative evaluation between two nutritional supplements in the improvement of telogen effluvium
Flávia Alvim Sant'Anna Addor1, Ludmila Coelho Donato2, Camila Sirieiro Abreu Melo2
1MEDCIN Research, Osasco, Brazil, flavia.addor@medcin.com.br.
Clinical, Cosmetic and Investigational Dermatology
|September 22, 2018
Summary
Nutritional supplements significantly improved telogen effluvium (TE) symptoms like hair loss and volume within 180 days. One supplement showed earlier improvements and better trichoscopy results than the other.
Area of Science:
- Dermatology
- Nutritional Science
- Trichology
Background:
- Telogen effluvium (TE) is diffuse hair loss due to shortened anagen and precipitated telogen phases.
- Nutritional supplementation is crucial for TE linked to dietary deficiencies.
- This study compares two oral supplements for TE monotherapy efficacy.
Purpose of the Study:
- To compare the efficacy of two distinct oral nutritional supplements in treating telogen effluvium (TE).
- To evaluate clinical and trichoscopic improvements in TE patients receiving different supplement regimens.
Main Methods:
- Randomized clinical study involving adult female patients with TE.
- Group 1 received a supplement with zinc, biotin, iron, vitamins A, C, E, B complex, folic acid, magnesium, and amino acids (keratin, collagen).
- Group 2 received calcium pantothenate, cystine, thiamine nitrate, medicinal yeast, keratin, and aminobenzoic acid for 180 days, with clinical and digital trichoscopy evaluations.
Main Results:
- Significant clinical improvement (P<0.05) in hair loss, volume, density, shine, and strength observed in 180 days for both groups.
- Group 1 showed significant improvement in all parameters by 90 days; Group 2 did not improve hair shine or strength.
- Digital trichoscopy revealed significant improvement only in Group 1 (11.09% vs. 7.76%) after 180 days.
Conclusions:
- Nutritional deficiencies should be suspected in idiopathic TE.
- Supplementation with a combination of nutrients at recommended daily intake significantly improves TE within the first trimester.
- An effective, safe, and convenient supplement aids patient adherence and treatment success.
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