Related Experiment Video
Updated: Feb 5, 2026
08:40
Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection
Published on: August 23, 2022
6.2K
Quantifying the impact of inhalational burns: a prospective study
Si Jack Chong1, Yee Onn Kok1, Rosanna Xiang Ying Tay1
11Department of Plastic, Reconstructive and Aesthetic Surgery, Singapore General Hospital, Level 5, Academia, Singapore, 169865 Singapore.
Burns & Trauma
|September 22, 2018
Summary
Inhalational burn injuries significantly increase patient mortality, length of hospital stay, and the risk of complications such as acute kidney injury (AKI) and acute respiratory distress syndrome (ARDS). Early identification and management are crucial for improving outcomes in burn patients with inhalational injury.
Area of Science:
- Trauma Surgery
- Critical Care Medicine
- Burn Management
Background:
- Inhalational injury is a significant contributor to morbidity and mortality in burn patients.
- Understanding its impact on clinical outcomes, complications, and bacteriology is essential for effective patient care.
Purpose of the Study:
- To analyze the clinical outcomes, complications, and bacteriology associated with inhalational burn injuries.
- To compare these factors in patients with and without inhalational injury.
Main Methods:
- A prospective study conducted at a single burn center over 15 months.
- Inclusion criteria based on history, symptoms, and nasoendoscopy for inhalational injury diagnosis.
- Standardized criteria (Berlin, AKIN, ABA) used for diagnosing ARDS, AKI, and infections.
Main Results:
- Patients with inhalational burns experienced longer hospital stays, more surgeries, and higher mortality rates compared to those with cutaneous injury alone.
- Higher incidence of ARDS (48.6%), AKI (37.1%), bacteraemia (31.4%), pneumonia (37.1%), and burn wound infection (51.4%) in the inhalational injury group.
- *Acinetobacter baumannii* was the most common pathogen; Gram-negative bacteria predominated in tissue cultures from patients with inhalational injury.
Conclusions:
- Inhalational injury accompanying burns substantially elevates the risk of prolonged hospitalization, mortality, and severe complications.
- Complications include acute kidney injury (AKI), acute respiratory distress syndrome (ARDS), and various infections, including sepsis.
- The findings underscore the critical impact of inhalational injury on burn patient prognosis and necessitate focused management strategies.
Related Concept Videos
01:22Burn Injuries
4.4K
Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
4.4K
01:23Inhaled Medications
803
Inhaled medications are crucial for managing chronic obstructive pulmonary disease (COPD) and asthma. They are essential for effective treatment and control, ensuring optimal respiratory health and well-being. Inhaled medication delivers drugs directly to the lungs, providing a rapid onset of action and reducing systemic side effects compared to oral or injectable medications. Three primary types of inhalation devices are used to administer these medications: nebulizers, metered-dose inhalers...
803
01:24Pulmonary Ventilation: Inhalation
8.2K
Pulmonary ventilation is a vital process that ensures the exchange of oxygen and carbon dioxide in the lungs. It refers to the movement of air into and out of the lungs, enabling the body to obtain oxygen and remove waste carbon dioxide. In this article, we will explore the intricacies of pulmonary ventilation, including its underlying principles, mechanisms, and the interplay of pressures within the respiratory system.
Boyle's law becomes particularly pertinent when examining respiratory...
Boyle's law becomes particularly pertinent when examining respiratory...
8.2K
01:19Impact of Groups on Groups
250
Social psychologists analyze how groups influence one another, shaping social structures and interactions through both cooperation and competition. These dynamics manifest in various ways, ranging from economic partnerships to intergroup conflicts that shape societal structures and perceptions.Cooperation and Competition in Intergroup RelationsIntergroup relationships vary across contexts, sometimes fostering cooperation and mutual benefit while at other times leading to conflict and...
250
01:20Inhalational Anesthetics: Overview
1.1K
Inhalation anesthetics are drugs that induce general anesthesia upon inhalation. They work by increasing the sensitivity of GABAA receptors or inhibiting NMDA receptors, leading to a decrease in central nervous system activity. The depth of anesthesia can be rapidly adjusted by changing the concentration of the inhaled gas. Some common examples of inhalational anesthetics include volatile liquids like isoflurane, desflurane, sevoflurane and gases like xenon and nitrous oxide. Isoflurane, a...
1.1K
02:30Quantifying Work
24.4K
As a system undergoes a change, its internal energy can change, and energy can be transferred from the system to the surroundings, or from the surroundings to the system.
24.4K