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Gender differences in cardiology: is it time for new guidelines?

Susanna Sciomer1, Federica Moscucci1, Christian Cadeddu Dessalvi2

  • 1Dipartimento di Scienze Cardiovascolari, Respiratorie, Nefrologiche, Anestesiologiche e Geriatriche, Università di Roma 'Sapienza', Roma, Rome.

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Cardiovascular disease (CVD) is the leading cause of death for women globally but remains underestimated. Addressing gender-specific disparities in diagnosis, treatment, and prognosis requires updated, gender-based guidelines.

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Area of Science:

  • Cardiology
  • Women's Health
  • Health Disparities

Background:

  • Cardiovascular disease (CVD) is the primary cause of morbidity and mortality in women worldwide.
  • Despite its prevalence, CVD in women is significantly underestimated.
  • Existing knowledge gaps hinder effective CVD management in female populations.

Purpose of the Study:

  • To highlight the underestimation of cardiovascular disease (CVD) as a leading cause of death in women.
  • To underscore the gender-based disparities in CVD diagnosis, treatment, and prognosis.
  • To advocate for a gender-specific revision of current clinical guidelines.

Main Methods:

  • Review of current literature on CVD in women.
  • Analysis of gender-based differences in CVD presentation and outcomes.
  • Comparative assessment of existing clinical guidelines against gender-specific needs.

Main Results:

  • CVD is the leading cause of death for women globally.
  • Significant disparities exist in the diagnosis, treatment, and prognosis of CVD between men and women.
  • These disparities stem from biological differences and socioeconomic/cultural factors.

Conclusions:

  • An updated, gender-based approach to CVD guidelines is crucial.
  • Addressing underestimation and disparities is essential for improving women's cardiovascular health.
  • Further research and guideline revisions are needed to ensure equitable care.