Related Experiment Video
Updated: Feb 5, 2026

06:17
Expression and Purification of Virus-like Particles for Vaccination
Published on: June 2, 2016
22.8K
Vaccines on a Shelf: Vaccines in Development Often Sit Around Untested
Texas Medicine
|September 22, 2018
Summary
New vaccines for diseases in Texas and globally remain largely untested. This highlights a critical gap in vaccine development pipelines, potentially delaying public health interventions.
Area of Science:
- Vaccinology
- Public Health
- Epidemiology
Background:
- Many vaccines targeting prevalent and emerging diseases are in early development stages.
- A significant bottleneck exists in the progression of these vaccine candidates through rigorous testing phases.
Purpose of the Study:
- To investigate the status of vaccine candidates for diseases relevant to Texas and beyond.
- To identify the extent of under-testing in vaccine development pipelines.
Main Methods:
- Review of vaccine development databases.
- Analysis of clinical trial registries.
- Assessment of regulatory submission timelines.
Main Results:
- A substantial number of vaccine candidates are not advancing to critical testing stages.
- Delays in testing are observed across various disease categories, including infectious and chronic conditions.
Conclusions:
- The lack of comprehensive testing for numerous vaccine candidates poses a risk to timely disease control.
- Addressing this gap is crucial for strengthening public health preparedness and response capabilities.
Related Concept Videos
Vaccinations
51.7K
Overview
51.7K
Cancer Vaccines
1.1K
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
1.1K
Sustainable Development
15.1K
As the human population continues to grow and use resources, we must be mindful of our planet’s natural limits. Sustainable development provides a pathway to maintain and improve human life now while also ensuring that future generations will have the resources that they need. The long-term success of sustainability efforts rests on understanding the interplay between human actions and ecological systems.
15.1K
Development of the Lymphatic System
2.1K
The development of lymphatic tissues and vessels in embryonic life begins around the fifth week. These structures originate from the mesoderm layer, with lymph sacs emerging from developing veins.
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...
2.1K
Language Development
916
Children master language quickly and with relative ease, supported by both biological predisposition and reinforcement. B. F. Skinner (1957) proposed that language is learned through reinforcement, while Noam Chomsky (1965) argued that language acquisition mechanisms are biologically determined.
The critical period for language acquisition suggests that the ability to acquire language is at its peak early in life. As people age, this proficiency decreases. Language development begins very...
The critical period for language acquisition suggests that the ability to acquire language is at its peak early in life. As people age, this proficiency decreases. Language development begins very...
916
Development of Immunocompetence
903
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
903

