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In Vitro Thrombosis Test for Ventricular Assist Devices
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Ventricular Assist Device-Associated Infection.

Tee K Teoh1, Margaret M Hannan1

  • 1Department of Clinical Microbiology, Mater Misericordiae University Hospital, University College Dublin, Eccles Street, Dublin 7, Dublin, Ireland.

Infectious Disease Clinics of North America
|September 23, 2018
PubMed
Summary
This summary is machine-generated.

Ventricular assist devices (VADs) improve survival for end-stage heart failure. However, VAD-associated infections are a significant concern, impacting patient morbidity and mortality. This review covers VAD infection management and prevention strategies.

Keywords:
DrivelineImplantable cardiac deviceNon-VAD infectionsVAD-related infectionsVAD-specific infections

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Area of Science:

  • Cardiology
  • Infectious Diseases
  • Biomedical Engineering

Background:

  • Heart transplantation is limited by donor availability.
  • Ventricular assist devices (VADs) are mechanical pumps supporting end-stage heart failure patients.
  • Increasing VAD survival rates are challenged by infection-related morbidity and mortality.

Purpose of the Study:

  • To review current concepts in VAD-associated infections.
  • To outline definitions, diagnosis, microbiology, and management principles.
  • To summarize VAD infection prevention strategies.

Main Methods:

  • Literature review of VAD-associated infections.
  • Synthesis of current knowledge on definitions, diagnosis, and microbiology.
  • Compilation of management and prevention strategies.

Main Results:

  • VAD infections present complex diagnostic and management challenges.
  • Understanding microbiology is crucial for effective treatment.
  • Proactive prevention strategies are essential for improving patient outcomes.

Conclusions:

  • VADs are vital for end-stage heart failure, but infection remains a critical complication.
  • Comprehensive management and robust prevention strategies are necessary to mitigate VAD-associated infections.
  • Further research into novel prevention and treatment methods is warranted.