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Related Concept Videos

Flow Cytometry01:23

Flow Cytometry

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The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
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Overview of Advanced Functional Groups02:22

Overview of Advanced Functional Groups

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Functional groups are groups of atoms with specific chemical properties that occur within organic molecules and are sometimes denoted as “R”. Functional groups can “functionalize” a compound by enabling it to adopt different physical and chemical properties.
Types of Advanced Functional Groups
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Extraction: Advanced Methods00:56

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Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
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Sample Preparation for Analysis: Advanced Techniques01:08

Sample Preparation for Analysis: Advanced Techniques

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Accurate analysis of complex samples often requires advanced preparation techniques to achieve reliable and reproducible results. Samples containing inorganic or organic materials can be challenging to dissolve or decompose effectively. Standard sample preparation methods include acid digestion, fusion, dry ashing, and wet digestion.
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Gene Flow02:39

Gene Flow

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Gene flow is the transfer of genes among populations, resulting from either the dispersal of gametes or from the migration of individuals.
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Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques01:30

Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques

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Airway management is essential in emergency and surgical medicine, ensuring ventilation and oxygenation in patients who cannot maintain their own airway. Clinicians use a range of techniques and devices to secure the airway, depending on the patient’s condition and the clinical context. Key methods include endotracheal intubation, rapid sequence intubation (RSI), supraglottic airway devices, and advanced visualization aids. In cases where these approaches fail, surgical airway...
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Related Experiment Video

Updated: Feb 5, 2026

Automation of the Micronucleus Assay Using Imaging Flow Cytometry and Artificial Intelligence
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Automation of the Micronucleus Assay Using Imaging Flow Cytometry and Artificial Intelligence

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New advances in microfluidic flow cytometry.

Yanli Gong1, Na Fan1, Xu Yang1

  • 1School of Mechanical and Electrical Engineering, University of Electronic Science and Technology of China, Chengdu, P. R. China.

Electrophoresis
|September 23, 2018
PubMed
Summary
This summary is machine-generated.

Portable microfluidic flow cytometry offers advanced point-of-care diagnostics. This technology enables rapid, multi-characteristic analysis of biological samples, improving healthcare access in remote regions.

Keywords:
Flow cytometryMicrofabricationMicrofluidic flow cytometryMicrofluidics

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Area of Science:

  • Biomedical Engineering
  • Analytical Chemistry
  • Point-of-Care Diagnostics

Background:

  • Microfluidic flow cytometry integrates microfluidics and flow cytometry for novel on-chip functionalities.
  • Portable, low-cost, and compact flow cytometers are crucial for healthcare in underserved regions like Africa and Asia.

Purpose of the Study:

  • To review recent advancements in microfluidic flow cytometry for point-of-care testing.
  • To examine the challenges and future directions in the field.

Main Methods:

  • Review of microfluidic techniques for sample manipulation (pumping, focusing, sorting).
  • Exploration of novel detection approaches for biological samples.
  • Analysis of data processing methods in microfluidic flow cytometry.

Main Results:

  • Significant progress in microfluidic sample handling and detection methods.
  • Development of integrated systems for comprehensive biological sample analysis.
  • Identification of key challenges hindering widespread adoption.

Conclusions:

  • Microfluidic flow cytometry is a rapidly advancing field with potential for significant healthcare impact.
  • Further research is needed to overcome current challenges and enhance device portability and cost-effectiveness.
  • The technology holds promise for democratizing advanced diagnostics globally.