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Evolution and Current Trends in the Management of Acute Appendicitis
Michel Wagner1, Dustin John Tubre2, Juan A Asensio3
1Division of Trauma Surgery and Surgical Critical Care, Department of Surgery, Creighton University School of Medicine, Creighton University Medical Center, 7710 Mercy Road #2000, Omaha, NE 68124, USA; Department of Translational Science, Creighton University School of Medicine, Creighton University Medical Center, 7500 Mercy Road, Omaha, NE 68124, USA.
Appendicitis treatment has evolved from surgery to nonoperative management, with renewed interest in conservative approaches. Advances in diagnostics and microbiome research are influencing current appendicitis care strategies.
Area of Science:
- Surgical innovation and medical diagnostics
Background:
- The historical treatment of appendicitis has seen significant evolution since the first appendectomy.
- Management strategies have shifted from early surgical interventions to open and minimally invasive surgeries.
- There is a resurgence in interest in nonoperative management for acute appendicitis.
Purpose of the Study:
- To review the historical and current management trends in appendicitis.
- To highlight the impact of diagnostic advancements on appendicitis care.
- To explore emerging research into the role of the appendix microbiome.
Main Methods:
- Review of historical surgical and nonoperative treatment modalities for appendicitis.
- Analysis of the influence of diagnostic scoring systems and medical imaging.
- Consideration of current scientific investigations into appendiceal microbiome.
Main Results:
- Appendicitis treatment has cycled from nonoperative to surgical and back to nonoperative management.
- Diagnostic scoring systems and advanced imaging have refined acute appendicitis diagnosis.
- The role of the appendix microbiome in appendicitis is an area of active scientific inquiry.
Conclusions:
- Appendicitis management is dynamic, influenced by historical context and technological advancements.
- Nonoperative management is regaining prominence in the treatment paradigm for acute appendicitis.
- Future research directions include understanding the microbiome's impact on appendicitis.
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