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Updated: Feb 4, 2026

Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos
Published on: September 9, 2015
Mycobacterium abscessus infection in a spa worker
Miguel Costa-Silva1, Artur César1, Preto Gomes Nuno1
1Department of Dermatology and Venereology, Centro Hospitalar São João, EPE, Porto, Portugal.
Mycobacterium abscessus (M. abscessus) can cause skin infections, often linked to environmental exposure like tap water. Early diagnosis via biopsy and culture is crucial for managing these rare, but serious, cutaneous ulcers.
Area of Science:
- Medical Microbiology
- Dermatology
- Infectious Diseases
Background:
- Mycobacterium abscessus (M. abscessus), a non-tuberculous mycobacterium, is increasingly recognized as a human pathogen.
- This bacterium is ubiquitous in the natural environment, posing a risk for infection through various exposure routes.
Observation:
- A case of a skin ulcer caused by M. abscessus in a spa worker is presented.
- Contamination often occurs via tap water, though outbreak sources remain frequently unidentified.
- Cutaneous ulcers, particularly in trauma-prone areas, necessitate considering non-tuberculous mycobacterial infections in differential diagnoses.
Findings:
- Early diagnosis of M. abscessus skin infections relies on biopsies and mycobacterium cultures.
- No standardized treatment exists for M. abscessus skin infections; management is individualized based on host immunity and disease severity.
Implications:
- Highlights the importance of considering M. abscessus in the differential diagnosis of unexplained cutaneous ulcers.
- Emphasizes the need for prompt microbiological investigation for effective patient management.
- Suggests potential environmental sources, such as tap water, in M. abscessus outbreaks.
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