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Published on: January 12, 2018
Late preterms: are they all the same?
Manuel R G Carrapato1,2, Tatiana Pereira1, Cláudia Silva2,3
1São Sebastião Hospital, Santa Maria Feira, Portugal.
Insights
Late preterm infants (LPT) are not a uniform group. Identifying distinct subgroups of LPT neonates is crucial for understanding their varied health outcomes and care needs.
Area of Science:
- Neonatology
- Perinatal Medicine
- Public Health
Background:
- Late preterm infants (LPT), born between 34 and 36 weeks gestation, constitute a significant majority of preterm births.
- Despite lower mortality rates compared to very preterm infants, LPT neonates face increased neonatal morbidities, imposing substantial burdens.
- The incidence of LPT births has risen in recent years, necessitating a deeper understanding of this population.
Purpose of the Study:
- To investigate whether late preterm infants (LPT) represent a homogenous group.
- To differentiate LPT neonates based on their pre- and postnatal circumstances.
- To identify distinct classes of LPT neonates and their potential behavioral differences.
Main Methods:
- Classification of late preterm infants (LPT) into distinct subgroups based on birth circumstances.
- Analysis of spontaneous late preterms (SpLPT), induced LPT (IdLPT), and postponed delivery LPT (PtLPT).
- Comparison of behavioral and clinical characteristics across identified LPT subgroups.
Main Results:
- Late preterm infants (LPT) are not a uniform group, despite similar gestational ages.
- Three distinct classes of LPT neonates were identified: spontaneous (SpLPT), induced (IdLPT), and postponed delivery (PtLPT).
- These LPT subgroups exhibit different behaviors and may require tailored medical approaches.
Conclusions:
- Late preterm infants (LPT) exhibit significant heterogeneity.
- Recognizing distinct LPT subgroups (SpLPT, IdLPT, PtLPT) is essential for appropriate clinical management.
- Further research into the specific needs and outcomes of each LPT class is warranted.
Abstract:
Very preterm infants (VPT) and, especially extreme low gestational age (ELGA) preterms, often on the threshold of viability, make the headlines of both, the scientific as well as the popular press. However, all together they represent between 1 and 2% of all livebirths. Late preterms (LPT) those born between 34/07 and 36/06 weeks, on the other hand, may account for up to 80% of all preterms and for some 5-8% of all births. Although mortality is low they are prone to increasing neonatal morbidities posing a considerable medical, financial and psychosocial burden. In the last years, for many reasons, LPT appear to have increased considerably throughout the western world. But are LPT neonates all the same? In spite of overlapping gestational ages (GA) LPT may behave quite differently depending on circumstances surrounding their pre- and postnatal events. We can identify three different classes of LPT neonates: spontaneous late preterms (SpLPT) born in the absence of previous maternal illnesses and/or pregnancy related disorders; Induced LPT (IdLPT) due to maternal/fetal complications and those babies being born after 34-week gestation from postponed delivery at an earlier GA (PtLPT) - and they are quite different babies, with different behavior, despite a common and same gestational age.
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