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Association between cognitive function and life-space mobility in older adults: results from the FRéLE longitudinal
François Béland1,2,3, Dominic Julien4,5,6, Nathalie Bier7,8
1Groupe de recherche Solidage, CSSS de la Montagne, site Metro, 1801, boulevard de Maisonneuve Ouest, bureau 600, Montréal, Québec, H3H 1J9, Canada. francois.beland@umontreal.ca.
BMC Geriatrics
|September 26, 2018
Summary
Cognitive function
Area of Science:
- Gerontology
- Neuroscience
- Public Health
Background:
- Conflicting findings exist on the link between cognition and life-space mobility in older adults.
- Mediators and moderators of this association remain underexplored.
Purpose of the Study:
- To examine the relationship between cognition and life-space mobility in older adults.
- To identify intervening variables influencing this association.
Main Methods:
- Longitudinal study with 1643 community-dwelling older adults (≥65 years) over 2 years.
- Growth mixture models used for mediation and moderation analyses.
- Assessed cognitive function, life-space mobility, depressive symptoms, locus of control, gait speed, and grip strength.
Main Results:
- Initial cognitive function's association with life-space was mediated by depressive symptoms and gait speed.
- Grip strength moderated the initial association between cognition and life-space mobility.
- No direct link found between changes in cognition and life-space mobility over 2 years; changes in depressive symptoms mediated this relationship.
Conclusions:
- The relationship between changes in cognitive function and life-space mobility in older adults is unclear over a 2-year period.
- Depressive symptoms play a mediating role in the longitudinal association.
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