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Updated: Feb 4, 2026
Quantitative Analysis of Chromatin Proteomes in Disease
Published on: December 28, 2012
SanXoT: a modular and versatile package for the quantitative analysis of high-throughput proteomics experiments
Marco Trevisan-Herraz1,2, Navratan Bagwan1, Fernando García-Marqués1,2
1Vascular Pathophysiology Area, Cardiovascular Proteomics Laboratory, Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain.
Summary:
Mass spectrometry-based proteomics has had a formidable development in recent years, increasing the amount of data handled and the complexity of the statistical resources needed. Here we present SanXoT, an open-source, standalone software package for the statistical analysis of high-throughput, quantitative proteomics experiments. SanXoT is based on our previously developed weighted spectrum, peptide and protein statistical model and has been specifically designed to be modular, scalable and user-configurable. SanXoT allows limitless workflows that adapt to most experimental setups, including quantitative protein analysis in multiple experiments, systems biology, quantification of post-translational modifications and comparison and merging of experimental data from technical or biological replicates.
Availability And Implementation:
Download links for the SanXoT Software Package, source code and documentation are available at https://wikis.cnic.es/proteomica/index.php/SSP.
Contact:
jvazquez@cnic.es or ebonzon@cnic.es.
Supplementary Information:
Supplementary information is available at Bioinformatics online.
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