Related Experiment Video
Updated: Feb 4, 2026

Measuring Blood Pressure in Mice using Volume Pressure Recording, a Tail-cuff Method
Published on: May 15, 2009
Ambulatory versus clinic blood pressure measurement - more evidence
Insights
Ambulatory blood pressure monitoring is a more accurate predictor of mortality risk than traditional clinic blood pressure readings. This finding emphasizes the importance of using ambulatory monitoring for better cardiovascular risk assessment.
Area of Science:
- Cardiology
- Hypertension Research
- Clinical Epidemiology
Background:
- Clinic blood pressure (BP) measurements are standard but may not accurately reflect a patient's usual BP.
- Ambulatory blood pressure monitoring (ABPM) offers a more comprehensive assessment of BP variations.
- The prognostic value of ABPM compared to clinic BP for mortality requires further clarification.
Purpose of the Study:
- To evaluate the association between clinic BP, ABPM, and all-cause mortality.
- To determine which BP measurement method provides superior risk prediction for mortality.
Main Methods:
- Systematic review and meta-analysis of observational studies.
- Inclusion of studies comparing clinic BP and ABPM with mortality outcomes.
- Statistical analysis to assess hazard ratios for different BP measurement types.
Main Results:
- Both clinic and ambulatory blood pressure measurements were associated with mortality.
- Ambulatory blood pressure monitoring demonstrated a stronger and more consistent association with mortality risk across various metrics.
- Systolic and diastolic ambulatory BP were significant predictors of mortality, outperforming clinic BP.
Conclusions:
- Ambulatory blood pressure monitoring provides more accurate prognostic information regarding mortality than standard clinic measurements.
- Clinical guidelines should consider incorporating ABPM for improved cardiovascular risk stratification.
- Further research into the clinical implementation of ABPM is warranted.
Abstract:
Review of: Banegas J et al. Relationship between clinic and ambulatory blood pressure measurements and mortality. New Engl J Med 2018; 378: 1509-20.
Related Concept Videos
Measurement of Blood Pressure
Equipments Used To Measure Blood Pressure
This invasive approach involves cannulating a peripheral artery. During each cardiac contraction, pressure generates mechanical motion within the catheter, transmitted through rigid, fluid-filled tubing to a transducer. This transducer converts mechanical motion into electrical signals displayed as waveforms on a monitor. An automatic flushing system prevents blood backflow. Due to the potential risk of unexpected arterial blood loss, this method is primarily used in intensive...
Special considerations while measuring blood pressure
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
The Evidence for Evolution
Blood Pressure
Blood Pressure
The average BP in an adult is typically around 120/80 mmHg (millimeters of mercury). In this measurement, the numerator (120) indicates the systolic pressure, which is the pressure in the arteries during the contraction of the heart's ventricles as blood is expelled. The denominator (80) represents the...

