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Related Experiment Videos

Primary bilateral breast cancer.

E B Smith

    Journal of the National Medical Association
    |November 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    This study on bilateral breast cancer found a 7.1% incidence and a 51% disease-free survival rate over 25 years. Diagnosis involved self-exams, physical exams, and mammography, with biopsy for suspicious masses.

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    Area of Science:

    • Oncology
    • Radiology
    • Surgical Pathology

    Background:

    • Bilateral breast cancer presents a unique diagnostic and management challenge.
    • Understanding the incidence and survival rates of synchronous and metachronous primary breast cancer is crucial for patient outcomes.

    Purpose of the Study:

    • To analyze the incidence, diagnosis, and survival rates of bilateral breast cancer.
    • To evaluate the effectiveness of diagnostic methods and treatment strategies for contralateral breast cancer.

    Main Methods:

    • Retrospective review of 1,148 primary breast cancers diagnosed between 1960-1980.
    • Analysis of diagnostic approaches including breast self-examination, clinical examination, mammography, and biopsy.
    • Evaluation of disease-free survival rates for patients with invasive bilateral breast cancers.

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    Main Results:

    • An incidence of 7.1% for synchronous and metachronous invasive primary breast cancer was observed.
    • Noninvasive breast cancer accounted for 1.8% of the total cases.
    • The 5- to 25-year disease-free survival rate for 82 invasive bilateral breast cancers was 51%.

    Conclusions:

    • Diagnostic strategies for contralateral breast cancer should include self-examination, clinical assessment, and mammography, with biopsy for discrete masses.
    • "Blind focal biopsy" of the contralateral breast is not recommended.
    • Survival outcomes for bilateral breast cancer were less grave than anticipated when compared to unilateral cases.