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Updated: Feb 4, 2026

Invasive Hemodynamic Characterization of the Portal-hypertensive Syndrome in Cirrhotic Rats
Published on: August 1, 2018
[IMMEDIATE RESULTS OF MESOCAVAL SHUNTING IN SURGICAL TREATMENT OF PORTAL HYPERTENSION IN CHILDREN]
Insights
Mesocaval shunting (MCSH) effectively treats pediatric portal hypertension (PH), significantly reducing gastroesophageal varices hemorrhage. This surgical approach offers a higher success rate compared to disconnecting operations.
Area of Science:
- Pediatric Surgery
- Hepatology
- Vascular Surgery
Background:
- Portal hypertension (PH) in children often leads to severe gastroesophageal varices and hemorrhage.
- Surgical interventions are crucial for managing PH complications in pediatric patients.
- Previous surgical methods, like disconnecting operations, have shown limited efficacy.
Purpose of the Study:
- To analyze the efficacy of mesocaval shunting (MCSH) in treating portal hypertension (PH) in a pediatric cohort.
- To evaluate MCSH as a treatment option, particularly for recurrent hemorrhage.
- To compare the outcomes of MCSH with traditional disconnecting operations.
Main Methods:
- Retrospective analysis of 69 children treated for portal hypertension.
- Mesocaval shunting (MCSH) was performed, with hemorrhage from gastroesophageal varices as the primary indication.
- MCSH was utilized as a reoperation in 53.6% of cases.
Main Results:
- Mesocaval shunting (MCSH) achieved an average decompression of the portal vein system in 30.9% of patients.
- The overall efficacy of surgical treatment for PH using MCSH reached 85.5%.
- This represents a significant improvement compared to the 36% efficacy observed after disconnecting operations.
Conclusions:
- Mesocaval shunting (MCSH) is a highly effective surgical treatment for pediatric portal hypertension (PH).
- MCSH significantly improves outcomes and reduces hemorrhage in children with PH, especially when compared to disconnecting procedures.
- The reoperation rate indicates MCSH's utility in complex or previously treated cases.
Abstract:
Efficacy of mesocaval shunting (МCSH) in the treatment of portal hypertension (PH) in 69 children was analyzed. The occurrence of hemorrhage from the gastroesophageal varicosely—changed veins, served as the main indication for the MCSH application. МCSH was applied in 53.6% patients as a reoperation variant; it guarantees decompression of a portal vein system — by 30.9% at average. Application of MCSH permits to raise efficacy of surgical treatment of PH in children up to 85.5%, comparing with such after disconnecting operations (36%).
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