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Updated: Feb 4, 2026

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Determining the Phagocytic Activity of Clinical Antibody Samples
Published on: November 30, 2011
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[INDICATORS OF PHAGOCYTIC ACTIVITY OF MONOCYTES AND CYTOKINE PROFILE IN PATIENTS WITH ERYSIPELAS OF VARYING SEVERITY]
Klinichna Khirurhiia
|September 27, 2018
Summary
Erysipelas treatment using immunomodulators improved monocyte phagocytic activity. This study investigated the immunological effects of immunomodulator application in 51 erysipelas patients.
Area of Science:
- Immunology
- Infectious Diseases
Background:
- Erysipelas is a severe bacterial infection with high complication and mortality rates.
- Immunological dysregulation is implicated in the pathogenesis of erysipelas.
Purpose of the Study:
- To investigate the immunological effects of immunomodulator application in patients with erysipelas.
- To assess changes in phagocytic activity of monocytes (PHAM) and cytokine profiles during treatment.
Main Methods:
- Immunological investigations were conducted on 51 patients diagnosed with erysipelas.
- Patients received complex treatment including immunomodulator application.
Main Results:
- Significant alterations in the indices of phagocytic activity of monocytes (PHAM) were observed in erysipelas patients.
- Changes in the cytokine profile were also noted in patients undergoing treatment.
Conclusions:
- The application of immunomodulators in complex erysipelas treatment demonstrated a positive impact on PHAM indices.
- Immunomodulatory therapy may be a beneficial adjunct in managing erysipelas by enhancing immune responses.
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