Bioinspired Catalytic Generation of Main-group Electrophiles by Cooperative Bond Activation
Francis Forster1, Martin Oestreich2
1Institut für Chemie Technische Universität Berlin Straße des 17. Juni 115, 10623 Berlin, Germany.
Abstract:
Catalytic processes involving cooperativity have seen tremendous progress in recent years and impressive new synthetic methodologies have been developed. Inspired by the cooperative heterolytic H₂ splitting in [NiFe] hydrogenases, Ohki and Tatsumi designed cationic ruthenium thiolate complexes with a tethered sulfur ligand. Over the last decade, we have demonstrated the facile activation of main-group hydrides such as hydrosilanes, hydroboranes, DIBAL-H, and hydrostannanes by the Ru-S bond in Ohki-Tatsumi complexes. This account illustrates these E-H bond activations and highlights selected catalytic applications, particularly dehydrocouplings, of the generated main-group electrophiles.
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