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Updated: Feb 4, 2026

Author Spotlight: Experimental Approaches for the Synthesis of Low-Valent Metal-Organic Frameworks from Multitopic Phosphine Linkers

Author Spotlight: Experimental Approaches for the Synthesis of Low-Valent Metal-Organic Frameworks from Multitopic Phosphine Linkers

Published on: May 12, 2023

Phosphine Organocatalysis.

Hongchao Guo¹, Yi Chiao Fan², Zhanhu Sun¹

¹Department of Applied Chemistry , China Agricultural University , Beijing 100193 , P. R. China.

Chemical Reviews

|September 28, 2018

Summary

This summary is machine-generated.

This review classifies nucleophilic phosphine catalysis based on electrophilic components, primarily those with carbon-carbon multiple bonds like alkenes and alkynes. It organizes reactions by nucleophile type and covers related phosphine-ylide formation.

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Last Updated: Feb 4, 2026

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Area of Science:

Organic Chemistry
Catalysis
Organophosphorus Chemistry

Background:

Nucleophilic phosphine catalysis is initiated by phosphine addition to electrophiles, forming zwitterionic intermediates under mild conditions.
Understanding the classification of these reactions is crucial for advancing synthetic methodologies.

Purpose of the Study:

To systematically review and classify nucleophilic phosphine catalysis reactions.
To organize reactions based on the nature of the electrophilic component and the coreactant.

Main Methods:

Classification of reactions based on electrophilic starting materials, including those with carbon-carbon multiple bonds (alkenes, allenes, alkynes, MBHADs).
Categorization of reactions by the type of coreactant (nucleophiles, dinucleophiles, electrophiles, electrophile-nucleophiles).
Inclusion of related reactions such as phosphine-ylide formation and miscellaneous topics.

Main Results:

A comprehensive classification of nucleophilic phosphine catalysis is presented, focusing on electrophilic components.
Reactions are detailed according to the presence or absence of carbon-carbon multiple bonds in the electrophile.
Related catalytic and non-catalytic phosphine-involved transformations are discussed.

Conclusions:

This review provides a structured overview of nucleophilic phosphine catalysis, aiding in the understanding and development of new synthetic routes.
The classification highlights the versatility of phosphines as catalysts in organic synthesis.