Copper-Catalyzed Decarboxylative Cascade Annulation of Propargylic Cyclic Carbamates with Allenediones
Rongbin Li1, Mengxi Lu1, Bing Zheng1
1Department of Chemistry, China Agricultural University, Beijing 100193, P. R. China.
Abstract:
A copper-catalyzed decarboxylative cascade annulation reaction of 5-ethynyloxazolidine-2,4-diones and allenediones has been developed. This protocol affords a new class of pyranofuran derivatives in moderate to high yields with good Z/E selectivity. A proposed mechanism indicated that the reaction undergoes a cascade [4+1] annulation/intramolecular cyclization reaction. This cascade process underscores the promising potential of copper-allenylidenes in the construction of complex fused ring systems through cascade annulation.
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