Related Experiment Video
Updated: Feb 4, 2026
11:12
Registration of Calcium Transients in Mouse Neuromuscular Junction with High Temporal Resolution using Confocal Microscopy
Published on: December 1, 2021
2.4K
Resolution and registration in dual-plane co-RASOR MR
Evan McNabb1, Raimond Wong2,3,4, Michael D Noseworthy1,5,6,7,8,9
1McMaster School of Biomedical Engineering, McMaster University, Hamilton, Ontario, Canada.
Physics in Medicine and Biology
|September 28, 2018
Summary
A new MRI sequence, co-RASOR, accurately locates gold fiducial markers for MR-only radiation therapy planning. This method achieves high resolution and registration accuracy, enabling precise treatment delivery.
Area of Science:
- Medical Physics
- Radiology
- Oncology
Background:
- Magnetic resonance imaging (MRI) offers superior soft tissue contrast over computed tomography (CT).
- Advances in MRI equipment and pseudo-CT estimation facilitate MR-only radiation therapy planning.
- Gold fiducial markers (GFMs) are commonly used for localizing targets in radiation therapy.
Purpose of the Study:
- To evaluate the resolution and registration accuracy of a dual-plane co-RASOR MRI sequence for localizing implanted GFMs.
- To assess the feasibility of using co-RASOR for MR-only radiation therapy planning.
Main Methods:
- A fast, dual-plane co-RASOR sequence was employed to image GFMs in phantom and tissue.
- Off-resonant reconstructions were used to assess GFM resolution.
- Registration accuracy to CT images was evaluated using an MR-compatible phantom and a porcine sample phantom.
Main Results:
- Co-RASOR images resolved GFMs down to 5 mm apart at a 12 cm field of view.
- MR to CT registration errors showed standard deviations < 0.5 mm in all directions.
- Registration accuracy in a porcine phantom was acceptable, with a target registration error < 0.75 mm.
Conclusions:
- The dual-plane co-RASOR sequence provides high resolution and accurate registration of GFMs.
- This sequence is suitable for MR-only radiation therapy planning, enabling both registration and image tracking.
Related Concept Videos
01:11Work Done Over an Inclined Plane
4.0K
The center-of-mass framework helps to easily describe the work done on rigid bodies. Since the internal forces in a rigid body do no work, they can be ignored, and the external forces can be considered in the work-energy theorem.
The work done by gravity to move a rigid body, or the work done by an opposing force to move a rigid body against gravity, can be calculated using the center-of-mass framework. It is the line integral of the force of gravity over the path, considered positive if...
The work done by gravity to move a rigid body, or the work done by an opposing force to move a rigid body against gravity, can be calculated using the center-of-mass framework. It is the line integral of the force of gravity over the path, considered positive if...
4.0K
01:06Body Planes
32.1K
Body planes in anatomy are imaginary flat surfaces used as reference points to divide the body into sections for anatomical study. These planes are essential for understanding the orientation, relationships, and spatial organization of anatomical structures.
The sagittal plane is the plane that divides the body or an organ vertically into right and left sides. If this vertical plane runs directly down the middle of the body resulting in equal division, it is called the midsagittal or median...
The sagittal plane is the plane that divides the body or an organ vertically into right and left sides. If this vertical plane runs directly down the middle of the body resulting in equal division, it is called the midsagittal or median...
32.1K
01:21Coordinate Plane
365
The Cartesian coordinate plane is a fundamental structure in mathematics that enables the visualization of relationships between numerical values in two dimensions. It is formed by two intersecting number lines: a horizontal x-axis and a vertical y-axis. These axes meet at the origin, the point where both values are zero. Their intersection divides the plane into four quadrants labeled in a counterclockwise direction starting from the upper right.An ordered pair of numbers represents every...
365
01:30Plane Electromagnetic Waves I
5.1K
The existence of combined electric and magnetic fields that propagate through space as electromagnetic (EM) waves is the most significant prediction of Maxwell's equations. As Maxwell's equations hold in free space, the predicted electromagnetic waves do not require a medium for their propagation. An EM wave comprises an electric field, defined as the force per charge on a stationary charge, and a magnetic field, which is the force per charge on a moving charge.
The EM field is assumed to be a...
The EM field is assumed to be a...
5.1K
01:29Plane Electromagnetic Waves II
4.1K
Consider a plane wavefront traveling in position x-direction with a constant speed. This wavefront can be utilized to obtain the relationship between electric and magnetic fields with the help of Faraday's law.
4.1K
01:18Transformation of Plane Stress
748
Studying stress transformation is essential in understanding how stress components within a material, like a cube under plane stress, change with rotation. This change is analyzed by considering a prismatic element within the cube. As the element rotates, the stress components acting on it—both normal and shearing stresses—change in magnitude and orientation. This change is quantified using trigonometric functions of the rotation angle, relating the forces acting on the rotated element's...
748