Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Lung Capacity01:47

Lung Capacity

56.3K
The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.
56.3K
Pleura of the Lungs01:13

Pleura of the Lungs

7.4K
The lungs are nestled in a cavity, shielded by the pleura. The pleura, a form of serous membrane, wraps around each lung. This membrane arrangement consists of two layers: the visceral and parietal pleurae. The visceral pleura lines the surface of the lungIn contrast, the parietal pleura is the outer layer and contacts to the thoracic wall, the mediastinum, and the diaphragm. The hilum is the point of connection between the visceral and parietal layers. The space between the parietal and...
7.4K
Gross Anatomy of the Lungs01:17

Gross Anatomy of the Lungs

4.7K
The lungs are a pair of vital organs connected to the trachea via the left and right bronchi. The base of these organs meets the dome-shaped muscle known as the diaphragm. Encased by the pleurae, the lungs contact the mediastinum. The right lung is shorter yet wider, and has a larger volume than the left lung. The left lung has an indentation known as the cardiac notch. The superior region of the lungs is referred to as the apex, whereas the base is the lower region near the diaphragm. The...
4.7K
Hybridoma Technology01:31

Hybridoma Technology

17.7K
Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
Hybridoma Selection
Commonly used fusion techniques — electroporation,...
17.7K
Natural and Artificial Concepts01:24

Natural and Artificial Concepts

572
In psychology, concepts can be divided into two categories: natural and artificial. Natural concepts are formed through direct or indirect experiences. For example, consider the concept of snow. If you live in a place with regular snowfall, such as Essex Junction, Vermont, you know snow through direct experiences. You’ve seen it fall, touched it, shoveled it, and played in it. You recognize its texture, appearance, and even its smell. In contrast, if you live on an island like Saint...
572
Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

3.7K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
3.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Outpatient Point-of-Care Cardiopulmonary Exercise Testing in Chronic Thromboembolic Pulmonary Disease: A Single-Center Experience.

JACC. Advances·2026
Same author

Coronary Artery Bypass Grafting to Acute Marginal Branch: Forgotten Coronary Artery.

Annals of thoracic surgery short reports·2026
Same author

Early Dynamic Changes in Haematoma Thickness in Medically Managed Type A Intramural Haematoma: A Multicentre Retrospective Study.

Interdisciplinary cardiovascular and thoracic surgery·2026
Same author

Early predictors and outcomes of mechanical circulatory support use during single lung transplant for secondary pulmonary hypertension: A large single-center experience.

JHLT open·2026
Same author

Declining Economic Burden of Coronary Atherosclerosis Relative to the United States Economic Output and Healthcare Sector Growth.

Cureus·2026
Same author

Off-Pump Lung Transplantation: Key Surgical and Anesthetic Considerations.

Annals of thoracic surgery short reports·2026

Related Experiment Video

Updated: Feb 4, 2026

Artificial Lung Device Priming for In Situ Fiber Bundle Surface Grafting
08:53

Artificial Lung Device Priming for In Situ Fiber Bundle Surface Grafting

Published on: March 28, 2025

801

Artificial Lungs for Lung Failure: JACC Technology Corner.

Noritsugu Naito1, Keith Cook1, Yoshiya Toyoda2

  • 1Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania.

Journal of the American College of Cardiology
|September 29, 2018
PubMed
Summary

Artificial lungs offer a promising alternative for patients with end-stage lung failure, addressing limitations of lung transplantation. Long-term artificial respiratory support could improve quality of life, similar to ventricular assist devices for heart failure.

Keywords:
artificial lungdestination therapyextracorporeal membrane oxygenationheart failurelung failuretransplantationventricular assist device

More Related Videos

Establishment of a Novel Ex Vivo Lung Perfusion System for Rat Lungs After Circulatory Death
09:14

Establishment of a Novel Ex Vivo Lung Perfusion System for Rat Lungs After Circulatory Death

Published on: October 18, 2024

1.0K
Author Spotlight: Enhancing Diagnostic Strategies and Biomarker Development for Comprehensive Lung Function Analysis
05:56

Author Spotlight: Enhancing Diagnostic Strategies and Biomarker Development for Comprehensive Lung Function Analysis

Published on: August 9, 2024

2.5K

Related Experiment Videos

Last Updated: Feb 4, 2026

Artificial Lung Device Priming for In Situ Fiber Bundle Surface Grafting
08:53

Artificial Lung Device Priming for In Situ Fiber Bundle Surface Grafting

Published on: March 28, 2025

801
Establishment of a Novel Ex Vivo Lung Perfusion System for Rat Lungs After Circulatory Death
09:14

Establishment of a Novel Ex Vivo Lung Perfusion System for Rat Lungs After Circulatory Death

Published on: October 18, 2024

1.0K
Author Spotlight: Enhancing Diagnostic Strategies and Biomarker Development for Comprehensive Lung Function Analysis
05:56

Author Spotlight: Enhancing Diagnostic Strategies and Biomarker Development for Comprehensive Lung Function Analysis

Published on: August 9, 2024

2.5K

Area of Science:

  • Biomedical Engineering
  • Pulmonology
  • Medical Devices

Background:

  • Lung transplantation is effective but limited for end-stage lung failure.
  • Ventricular assist devices have improved heart failure care.
  • No long-term artificial lung devices currently exist for destination therapy.

Purpose of the Study:

  • To review the history, current status, and future of artificial lungs.
  • To highlight the need for long-term artificial respiratory support as destination therapy.
  • To explore the potential of artificial lungs as analogous to ventricular assist devices.

Main Methods:

  • Literature review of artificial lung technology.
  • Analysis of current limitations in lung failure treatment.
  • Discussion of existing temporary solutions like extracorporeal membrane oxygenation.

Main Results:

  • Significant need exists for long-term artificial lung devices.
  • Artificial lungs could offer improved quality of life for advanced lung failure patients.
  • Extracorporeal membrane oxygenation serves as a temporary solution.

Conclusions:

  • Artificial lungs represent a critical area for future development in respiratory support.
  • Long-term artificial respiratory support could revolutionize care for end-stage lung failure.
  • The development of artificial lungs as destination therapy is a key future goal.