Related Experiment Video
Updated: Feb 4, 2026

12:45
Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer
Published on: February 12, 2022
6.6K
Redo transanal total mesorectal excision (Re-TaTME) after initial TaTME; is it possible?
Islam H Metwally1, José A Romero2, Pablo C Coello2
1Surgical Oncology Unit, Oncology Center Mansoura University (OCMU), Mansoura, Dakahlia, Egypt.
AME Case Reports
|September 29, 2018
Summary
Anastomotic stenosis after rectal cancer surgery can be serious. A minimally invasive abdominal and anal approach offers a potential treatment for this complication following transanal total mesorectal excision (TaTME).
Area of Science:
- Gastroenterology
- Surgical Oncology
- Colorectal Surgery
Background:
- Rectal cancer is a common malignancy requiring surgical resection.
- Anastomotic site stenosis is a significant post-operative complication following rectal resection.
- Current treatment options for anastomotic stenosis are still evolving.
Observation:
- A case of a male patient experiencing anastomotic stenosis after transanal total mesorectal excision (TaTME) for rectal cancer is presented.
- The patient underwent a minimally invasive abdominal and anal approach for the treatment of stenosis.
Findings:
- This report details a successful minimally invasive surgical intervention for anastomotic stenosis.
- The combined abdominal and anal approach addresses a challenging complication of rectal cancer surgery.
Implications:
- This technique provides a potential therapeutic option for surgeons managing anastomotic stenosis post-TaTME.
- Further consideration of this minimally invasive approach may improve patient outcomes in similar cases.
- Highlights the importance of innovative surgical techniques in managing rectal cancer complications.
Related Concept Videos
Base Excision Repair
26.4K
One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template.
The first step of...
The first step of...
26.4K
Base Excision Repair
5.1K
5.1K
Initiation of Translation
39.0K
Initiating translation is complex because it involves multiple molecules. Initiator tRNA, ribosomal subunits, and eukaryotic initiation factors (eIFs) are all required to assemble on the initiation codon of mRNA. This process consists of several steps that are mediated by different eIFs.
First, the initiator tRNA must be selected from the pool of elongator tRNAs by eukaryotic initiation factor 2 (eIF2). The initiator tRNA (Met-tRNAi) has conserved sequence elements including modified bases at...
First, the initiator tRNA must be selected from the pool of elongator tRNAs by eukaryotic initiation factor 2 (eIF2). The initiator tRNA (Met-tRNAi) has conserved sequence elements including modified bases at...
39.0K
Initiation of Translation
8.1K
8.1K
Nucleotide Excision Repair
40.9K
Overview
40.9K
Nucleotide Excision Repair
5.2K
DNA Distortion and Damage
Cells are regularly exposed to mutagens—factors in the environment that can damage DNA and generate mutations. UV radiation is one of the most common mutagens and is estimated to introduce a significant number of changes in DNA. These include bends or kinks in the structure, which can block DNA replication or transcription. If these errors are not fixed, the damage can cause mutations, which in turn can result in cancer or disease depending on which sequences are...
Cells are regularly exposed to mutagens—factors in the environment that can damage DNA and generate mutations. UV radiation is one of the most common mutagens and is estimated to introduce a significant number of changes in DNA. These include bends or kinks in the structure, which can block DNA replication or transcription. If these errors are not fixed, the damage can cause mutations, which in turn can result in cancer or disease depending on which sequences are...
5.2K

