[REMOTE RESULTS OF SURGICAL TREATMENT IN PATIENTS, SUFFERING LOCALLY SPREAD FORMS OF MALIGNANT PANCREATIC TUMORS]

Remote results of surgical treatment of patients, suffering locally spread forms of pancreatic malignancies (PM), using different approaches, were analyzed. In retrospective investigation were included 84 patients with PM and invasion of the main vessels. In the group І patients palliative operations were performed, including in a subgroup Іа— cryoablation of PM, in a subgroup Іb — palliative pancreatic resection with leaving the tumor on the main vessels intact; and in patients of group ІІ the tumor was resected radically, including in a sub* group ІІа—pancreatic resection or total pancreatectomy with resection of the main vessels, and in subgroup ІІb — pancreatic resection or total pancreatectomy with cryoablation of tumor, which was left on the main vessel. The one—year, three—years and five—years survival indices have constituted in a subgroup Іа, accordingly 74, 17 and 0% (survival median 16 mo); in a subgroup Іb — 70, 20 and 0% (survival median 20 mo); in a subgroup ІІа — 83, 49 and 21% (survival median 29 mo); in a subgroup ІІb — 73, 41 and 18% (survival median 26 mo). Difference between the general survival indices in subgroups Іа and ІІа, Іb and ІІа is statistically significant. Application of aggressive surgical tactics have permitted to improve the general survival indices of the patients.