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Intravenous Iron Therapy in Heart Failure
Natasha L Altman1, Amit Patel2
1Section of Advanced Heart Failure and Transplant, Division of Cardiology, Department of Medicine, University of Colorado Denver, 12631 East 17th Avenue, Aurora, CO 80045, USA.
Heart Failure Clinics
|September 30, 2018
Summary
Iron deficiency anemia negatively impacts heart failure prognosis. Intravenous iron repletion significantly improves quality of life and reduces hospitalizations in heart failure patients.
Area of Science:
- Cardiology
- Hematology
- Internal Medicine
Background:
- Iron deficiency anemia is a common comorbidity in heart failure patients.
- It is associated with a poorer prognosis and reduced quality of life.
Purpose of the Study:
- To review the complex mechanisms linking iron deficiency to heart failure.
- To examine the evidence supporting iron repletion in heart failure management.
Main Methods:
- Review of recent randomized clinical trials.
- Analysis of existing literature on iron deficiency and heart failure.
Main Results:
- Intravenous iron repletion demonstrated significant improvements in quality of life.
- Hospitalization rates were notably reduced following iron repletion therapy.
Conclusions:
- Iron deficiency significantly impacts heart failure, but repletion offers therapeutic benefits.
- Further research is needed to understand the long-term effects of intravenous iron, with ongoing trials.
Keywords:
AnemiaFerrous carboxymaltoseHeart failureIntravenous (IV) ironIron deficiencyPeak oxygen consumptionMore Related Videos
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