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Assessment of Current Epidemiology and Risk Factors Surrounding Brachial Plexus Birth Palsy
Joshua M Abzug1, Charles T Mehlman2, Jun Ying3
1Department of Orthopaedics, University of Maryland School of Medicine, Timonium, MD.
Insights
The incidence of brachial plexus birth palsy (BPBP) is decreasing, with shoulder dystocia remaining the primary risk factor. New research identifies hypotonia as a risk factor and highlights increased hospital stays and costs for affected infants.
Area of Science:
- Pediatric neurology
- Obstetrics
- Public health
Background:
- Brachial plexus birth palsy (BPBP) affects newborns, with over 50% lacking identifiable risk factors.
- Current incidence and associated healthcare costs for BPBP are not well-established.
Purpose of the Study:
- To determine the current incidence of BPBP.
- To assess known and novel risk factors, including hypotonia.
- To evaluate the impact of BPBP on length of hospital stay (LOS) and direct costs.
Main Methods:
- Analysis of the 1997-2012 Kids' Inpatient Database.
- Multivariable logistic regression to identify risk factors for BPBP.
- Evaluation of LOS and direct medical costs for affected infants.
Main Results:
- BPBP incidence declined from 1997 to 2012, with 0.9 per 1,000 live births in 2012.
- Shoulder dystocia is the leading risk factor; hypotonia is a newly identified risk factor.
- Infants with BPBP experienced ~20% longer LOS and ~40% higher direct costs.
Conclusions:
- The incidence of BPBP is decreasing.
- Shoulder dystocia remains the most significant risk factor for BPBP.
- BPBP is associated with increased hospital LOS and direct costs.
Purpose:
Brachial plexus birth palsy (BPBP) is common; however, the current incidence is unknown and more than 50% of infants with BPBP have no known risk factors. The purpose of this study was to determine the current incidence of BPBP, assess known risk factors, and evaluate hypotonia as a new risk factor, as well as estimate the length of stay (LOS) and direct costs of children with an associated BPBP injury.
Methods:
Data from the 1997 to 2012 Kids' Inpatient Database data sets were evaluated to identify patients with a BPBP injury and various risk factors. Evaluation of LOS data and direct costs was also performed. Multivariable logistic regression analysis was utilized to assess the association of BPBP with its known and previously undescribed risk factors.
Results:
The incidence of BPBP has steadily decreased from 1997 to 2012, with an incidence of 0.9 ± 0.01 per 1,000 live births recorded in 2012. Shoulder dystocia is the number 1 risk factor for the development of a BPBP injury. Hypotonia is a newly recognized risk factor for the development of BPBP. Fifty-five percent of infants with BPBP have no known perinatal risk factors. The initial hospital LOS is approximately 20% longer for children with a BPBP injury and the hospital stay direct costs are approximately 40% higher.
Conclusions:
The incidence of BPBP is decreasing over time. Shoulder dystocia continues to be the most common risk factor for sustaining a BPBP injury. Children with a BPBP injury have longer LOSs and hospital direct costs compared with children without a BPBP injury.
Type Of Study/Level Of Evidence:
Prognostic II.
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