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Legume consumption increase adiponectin concentrations among type 2 diabetic patients: A randomized crossover
Parvin Mirmiran1, Shabnam Hosseini2, Somayeh Hosseinpour-Niazi2
1Department of Clinical Nutrition and Dietetics, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Iran.
Background And Objective:
This randomized crossover clinical trial investigated the effects of substituting legumes for meat consumption in the therapeutic lifestyle change (TLC) diet on leptin and adiponectin concentrations among type 2 diabetic patients.
Material And Methods:
Thirty-one type 2 diabetic patients (24 women, age: 58.1±6.0 years) were randomly assigned to groups designated to consume a legume-free TLC diet or a legume-based TLC diet for 8 weeks. Both diets were similar except for the replacement of two servings of red meat with legumes 3 days per week in the legume-based TLC group. Leptin and adiponectin concentrations were measured at baseline and after the 8-week intervention.
Results:
The legume-based TLC diet significantly increased adiponectin concentrations in comparison with the legume-free TLC diet. There was no significant change in leptin concentrations after both intervention diets.
Conclusions:
Legumes increased serum adiponectin concentrations in type 2 diabetic patients. Registration number: IRCT201202251640N7.
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