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Updated: Feb 4, 2026

Isolation and Characterization of Human Umbilical Cord-derived Mesenchymal Stem Cells from Preterm and Term Infants
Published on: January 26, 2019
Valid serial length measurements in preterm infants permit characterization of growth patterns
Lara Pavageau1, Charles R Rosenfeld1, Roy Heyne1
1Division of Neonatal-Perinatal Medicine, Department of Pediatrics, UT Southwestern Medical Center, Dallas, TX, USA.
Background:
The lack of a valid and safe method for measuring length in critically ill preterm neonates has led to a primary focus on weight gain.
Local Problem:
Paucity of valid length measurements, precluding the accurate analysis of growth patterns.
Methods:
Quality improvement project among infants < 29 weeks or small for gestational age < 35 weeks with embedded validation of (1) a caliper (infantometer) for length measurements and (2) length measurements during the first week to estimate birth length.
Intervention:
Implementation of valid methods to measure length.
Results:
We validated infantometer measurements and first week length measurements. The percentage of neonates with valid measurements during the first week rose from 10% to 78%, resulting in increased identification of classifiable growth patterns from < 10% to 89%.
Conclusions:
By increasing the percentage of neonates with valid length measurements in the first week postnatal, we identified an increased number of neonates with classifiable growth abnormalities.
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Data Validation
Key parameters for method validation include:

