Related Experiment Video
Updated: Feb 4, 2026

Use of the Scissor-Type Knife During the Peroral Endoscopy Myotomy Procedure for the Treatment of Achalasia
Published on: March 3, 2023
Peroral Endoscopic Myotomy for Achalasia
Lara W Schaheen1, Manuel Villa Sanchez1, James D Luketich1
1Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, UPMC Presbyterian, Suite C-800, 200 Lothrop Street, Pittsburgh, PA 15213, USA.
Abstract:
Peroral endoscopic myotomy surgery is an incisionless, minimally invasive, natural orifice technique used to treat the symptoms of achalasia and other spastic disorders of the esophagus. Recent experience demonstrates that it can be performed safely by experienced esophageal surgeons and there are very good short-term outcomes comparable to laparoscopic myotomy. The rapid worldwide adoption of this technique demonstrates its potential to replace the current therapies available for achalasia. A cautionary note is important in that long-term outcomes are not yet available in terms of dysphagia and GERD symptoms.
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