Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Arteries of the Upper Limbs01:12

Arteries of the Upper Limbs

2.4K
The subclavian artery transitions into the axillary artery as it exits the chest and enters the axillary region. This artery is critical for supplying blood to the shoulder area, including the head of the humerus, through the humeral circumflex arteries. As the vessel continues into the upper arm or brachium, it becomes the brachial artery. This artery plays a key role in vascularizing the brachial region and bifurcates at the elbow into several branches. These branches include the deep...
2.4K
Veins of Upper Limbs01:17

Veins of Upper Limbs

4.2K
The human circulatory system, a marvel of biological engineering, is a complex network of vessels that transport blood throughout the body. Among these, the veins responsible for carrying blood from the upper limbs are divided into two categories: deep and superficial.
The deep venous system is primarily composed of the ulnar and radial veins. The ulnar vein, which drains the fingers through the superficial palmar venous arches, and the radial vein, which serves the palms via the deep palmar...
4.2K
Bones of the Upper Limb: Humerus01:19

Bones of the Upper Limb: Humerus

7.2K
The upper limb consists of the arm, forearm, wrist, and hand bones. The humerus is the single bone of the upper arm region. Proximally, it has a large, spherical, smooth head that articulates with the glenoid cavity of the scapula to form the glenohumeral or shoulder joint. The margin of the head is the anatomical neck, a residual epiphyseal plate. Laterally it extends to form bony projections called the greater tubercle and the lesser tubercle. Next to the tubercles is the surgical neck, a...
7.2K
Bones of the Upper Limb: Ulna01:15

Bones of the Upper Limb: Ulna

4.5K
The ulna and radius are parallel bones of the antebrachium or the forearm. The ulna lies medially and consists of a bony tip called the olecranon process at its proximal end. This hook-like projection articulates with the olecranon fossa of the humerus and forms the "hinged" ulnohumeral part of the elbow joint. This joint facilitates forearm extension and flexion while preventing its hyperextension. Similarly, the coronoid process, another bony projection on the proximal/anterior side...
4.5K
Bones of the Upper Limb: Radius01:09

Bones of the Upper Limb: Radius

4.8K
The radius is longer of the two bones that make up the human antebrachium or forearm. At the proximal end, the radius articulates with the capitulum of the humerus and the radial notch of the ulna to form the elbow joint. At the distal end, the radius articulates with the ulna via the ulnar notch, forming the distal radioulnar joint. Distally, the radius also attaches to the carpal wrist bones (scaphoid and lunate) to form the radiocarpal joint.
The radius has a nail-shaped head, and a...
4.8K
Clinically Relevant Drug Product Specifications: Methods of Establishment01:29

Clinically Relevant Drug Product Specifications: Methods of Establishment

220
Product specifications define the acceptable quality of a pharmaceutical product by ensuring identity, purity, potency, and strength. These specifications serve as benchmarks during development, manufacturing, and post-approval quality control. Clinically relevant specifications are particularly important because they directly relate to a drug's safety and efficacy in clinical use.Dissolution studies are critical biopharmaceutic tools that link in vitro behavior to in vivo performance. They...
220

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Age-Related Changes in Virtual Pivot Point Position and Variability During Pediatric Gait Development.

Children (Basel, Switzerland)·2026
Same author

A Full-Body Motion Capture Gait Dataset of Healthy Young Adults Walking Ramps Up and Down.

Scientific data·2026
Same author

Evaluating the impact of task-sequencing on cognitive and motor performance in MS: PASAT and 3-minute walk test order effects.

Frontiers in neurology·2025
Same author

The effect of age-related sensorimotor changes on step-down strategy: a predictive simulation study.

Scientific reports·2025
Same author

Validity of IMUs in Comparison to a Marker-Based-Motion Capture System for Spatio-Temporal Parameters During Wheelchair Propulsion.

Sensors (Basel, Switzerland)·2025
Same author

Cognitive-motor interference in multiple sclerosis revisited: a dual-task paradigm using wearable inertial sensors and the Paced Auditory Serial Addition Test.

Frontiers in neurology·2025

Related Experiment Video

Updated: Feb 4, 2026

Author Spotlight: Enhancing Post-Stroke Upper Limb Rehabilitation with Robotic Technologies for Improved Motor Recovery and Functional Outcomes
04:49

Author Spotlight: Enhancing Post-Stroke Upper Limb Rehabilitation with Robotic Technologies for Improved Motor Recovery and Functional Outcomes

Published on: September 6, 2024

1.5K

Motorized Biomechatronic Upper and Lower Limb Prostheses-Clinically Relevant Outcomes.

Knut Lechler1, Bertrand Frossard2, Lynsay Whelan3

  • 1Össur hf, R&D, Medical Office, Reykjavik, Iceland(∗).

PM & R : the Journal of Injury, Function, and Rehabilitation
|October 2, 2018
PubMed
Summary

Major limb amputations significantly impair daily life. Biomechatronic prostheses offer improved function and quality of life, but intuitive control remains a challenge for lower limb applications.

More Related Videos

Author Spotlight: Using Motor Imagery Brain-Computer Interface to Improve Motor and Cognitive Function in Stroke Patients
09:42

Author Spotlight: Using Motor Imagery Brain-Computer Interface to Improve Motor and Cognitive Function in Stroke Patients

Published on: September 1, 2023

2.1K
Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy
09:18

Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy

Published on: January 12, 2019

10.9K

Related Experiment Videos

Last Updated: Feb 4, 2026

Author Spotlight: Enhancing Post-Stroke Upper Limb Rehabilitation with Robotic Technologies for Improved Motor Recovery and Functional Outcomes
04:49

Author Spotlight: Enhancing Post-Stroke Upper Limb Rehabilitation with Robotic Technologies for Improved Motor Recovery and Functional Outcomes

Published on: September 6, 2024

1.5K
Author Spotlight: Using Motor Imagery Brain-Computer Interface to Improve Motor and Cognitive Function in Stroke Patients
09:42

Author Spotlight: Using Motor Imagery Brain-Computer Interface to Improve Motor and Cognitive Function in Stroke Patients

Published on: September 1, 2023

2.1K
Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy
09:18

Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy

Published on: January 12, 2019

10.9K

Area of Science:

  • Biomedical Engineering
  • Rehabilitation Science
  • Prosthetics and Orthotics

Background:

  • Major limb amputations cause severe impairments in activity, body structure, function, and participation.
  • Demographic trends indicate a growing population of amputees facing age-related and higher-level amputation challenges.
  • Prosthetic use positively impacts mobility and depression, enhancing amputees' quality of life.

Purpose of the Study:

  • To review biomechatronic developments in upper and lower limb prostheses.
  • To contextualize these advancements within amputation challenges and clinically relevant outcomes.
  • To highlight the current status and limitations of actively powered prostheses.

Main Methods:

  • Literature review of biomechatronic developments in upper and lower limb prostheses.
  • Analysis of evidence related to biomechanical issues for lower limb prostheses.
  • Examination of evidence concerning activities of daily living (ADL) and instrumental ADL for upper limb prostheses.

Main Results:

  • Actively powered upper limb prostheses are common, while their clinical use in lower limbs is limited.
  • Biomechatronic prostheses enhance functional restoration but lack intuitive user control.
  • Evidence for lower limb prostheses primarily focuses on biomechanics, while upper limb evidence addresses ADL and instrumental ADL.

Conclusions:

  • Biomechatronic prostheses represent a significant advancement in restoring lost physical functions for amputees.
  • Further research is needed to achieve intuitive user control, especially for lower limb applications.
  • Diverse outcome measures are employed to assess the clinical relevance of prosthetic interventions.