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Related Experiment Video

Updated: Feb 4, 2026

DiOLISTIC Labeling of Neurons from Rodent and Non-human Primate Brain Slices
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An Open Resource for Non-human Primate Imaging.

Michael P Milham1, Lei Ai2, Bonhwang Koo2

  • 1Center for the Developing Brain, Child Mind Institute, New York, NY 10022, USA; Center for Biomedical Imaging and Neuromodulation, Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA.

Neuron
|October 2, 2018
PubMed
Summary
This summary is machine-generated.

The PRIMatE Data Exchange (PRIME-DE) initiative aggregates non-human primate magnetic resonance imaging (MRI) data. This open-access resource aims to advance translational and comparative neuroscience research by sharing valuable neuroimaging datasets.

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Area of Science:

  • Neuroscience
  • Neuroimaging
  • Comparative Neuroscience

Background:

  • Non-human primate neuroimaging is crucial for translational and cross-species neuroscience.
  • Data acquisition is limited by specialized facilities and capabilities.
  • Advances in technology have outpaced data availability.

Purpose of the Study:

  • To address the challenge of limited non-human primate neuroimaging data.
  • To establish a consortium for aggregating and sharing these datasets.
  • To facilitate broader access to non-human primate MRI data.

Main Methods:

  • The PRIMatE Data Exchange (PRIME-DE) consortium was formed.
  • Independently acquired non-human primate MRI datasets were aggregated.
  • Data were openly shared via the International Neuroimaging Data-sharing Initiative (INDI).

Main Results:

  • The initial release includes 25 independent data collections.
  • Data were aggregated across 22 different sites.
  • A total of 217 non-human primates are included in the initial release.

Conclusions:

  • PRIME-DE provides a valuable resource for non-human primate neuroimaging research.
  • The initiative aims to accelerate translational and comparative neuroscience.
  • Consideration of unique analytical challenges in non-human primate MRI data is outlined.