Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Obsessive-Compulsive Disorder

Obsessive-Compulsive Disorder

Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...

Personality Disorders: Dependent and Obsessive-Compulsive

Personality Disorders: Dependent and Obsessive-Compulsive

Dependent personality disorder and obsessive-compulsive personality disorder are two separate psychological conditions that influence behavior, relationships, and overall life functioning. Though both involve maladaptive behaviors, their core characteristics and motivations differ significantly.
Dependent Personality Disorder
Dependent personality disorder is characterized by an excessive reliance on others to manage various aspects of life. Individuals with this disorder often struggle...

Intrinsically Disordered Proteins

Intrinsically Disordered Proteins

Intrinsically disordered proteins are a group of proteins that do not fold into specific three-dimensional structures. Their structural flexibility allows them to complement ordered proteins to perform functions that are inaccessible to rigid structures. They are more common in eukaryotes than prokaryotes and may either be exclusively intrinsically disordered or hybrid proteins, consisting of a mix of ordered and disordered regions. The absence of a rigid structure in these proteins can be...

Epilepsy and Seizures: Overview

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...

Bone Disorders

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...

Disorders of Erythrocytes

Disorders of Erythrocytes

Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Gender differences in depression, anxiety, and quality of life in Parkinson's disease before and after deep brain stimulation surgery: a multicentre cohort study.

BMJ neurology open·2025

Same author

Early post-deep brain stimulation psychiatric adverse events in Parkinson's disease: a narrative review.

Journal of neurology, neurosurgery, and psychiatry·2025

Same author

Transcranial magnetic stimulation for obsessive-compulsive disorder and post-traumatic stress disorder: A comprehensive systematic review and analysis of therapeutic benefits, cortical targets, and psychopathophysiological mechanisms.

Progress in neuro-psychopharmacology & biological psychiatry·2024

Same author

Cognitive correlates of psychopathology in functional/dissociative seizures and non-lesional epilepsy: An exploratory study.

Epilepsy & behavior : E&B·2024

Same author

Virtual reality in functional neurological disorder: a theoretical framework and research agenda for use in the real world.

BMJ neurology open·2024

Same author

Sociodemographic and clinical risk factors for suicidal ideation and suicide attempt in functional/dissociative seizures and epilepsy: a large cohort study.

BMJ mental health·2024

Same journal

Compound heterozygosity with <i>PRRT2</i>: Pushing the phenotypic envelope in genetic epilepsies.

Epilepsy & behavior case reports·2019

Same journal

Familial association of genetic generalised epilepsy with limb-girdle muscular dystrophy through a mutation in <i>CAPN3</i>.

Epilepsy & behavior case reports·2019

Same journal

Asymptomatic carotid acute dissection following focal status epilepticus.

Epilepsy & behavior case reports·2019

Same journal

Ictogenesis during sEEG evaluation after acute intracranial hemorrhage.

Epilepsy & behavior case reports·2019

Same journal

Surgically treated intracranial supratentorial calcifying pseudoneoplasms of the neuraxis (CAPNON) with drug-resistant left temporal lobe epilepsy: A case report and review of the literature.

Epilepsy & behavior case reports·2019

Same journal

Non-convulsive status epilepticus associated with neuronal intranuclear inclusion disease: A case report and literature review.

Epilepsy & behavior case reports·2019

See all related articles

Search research articles

Related Experiment Video

Updated: Feb 4, 2026

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

Published on: January 9, 2015

Epilepsy and concomitant obsessive-compulsive disorder.

Jacob S Bird^1,2, Emiy Shah¹, Paul Shotbolt^1,2

¹Institute of Psychiatry, Psychology and Neuroscience, 16 De Crespigny Park, Camberwell, London, SE5 8AB, United Kingdom of Great Britain and Northern Ireland.

Epilepsy & Behavior Case Reports

|October 2, 2018

Summary

This summary is machine-generated.

Epilepsy and obsessive-compulsive disorder (OCD) frequently co-occur, significantly impacting quality of life. Tailored, patient-specific treatments are crucial for managing these co-occurring conditions in people with epilepsy (PWE).

Keywords:

Cognitive Behavioural Therapy Epilepsy Obsessive–compulsive disorder Quality of life SSRI

More Related Videos

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

Protocol for Repetitive Transcranial Magnetic Stimulation with Symptom Provocation to Treat Obsessive-compulsive Disorder

Protocol for Repetitive Transcranial Magnetic Stimulation with Symptom Provocation to Treat Obsessive-compulsive Disorder

Published on: November 25, 2025

Related Experiment Videos

Last Updated: Feb 4, 2026

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder

Published on: January 9, 2015

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Exploring the Neural Correlates of Cognitive Reappraisal in Obsessive-Compulsive Disorder Using Task-based Functional Magnetic Resonance Imaging

Published on: March 14, 2025

Protocol for Repetitive Transcranial Magnetic Stimulation with Symptom Provocation to Treat Obsessive-compulsive Disorder

Protocol for Repetitive Transcranial Magnetic Stimulation with Symptom Provocation to Treat Obsessive-compulsive Disorder

Published on: November 25, 2025

Area of Science:

Neurology
Psychiatry
Clinical Psychology

Background:

Psychiatric comorbidities are prevalent in people with epilepsy (PWE), often causing greater distress than seizures.
While affective and psychotic disorders are recognized comorbidities, the association with obsessive-compulsive disorder (OCD) in PWE is less understood.

Observation:

This study identified ten people with epilepsy (PWE) who also have obsessive-compulsive disorder (OCD).
Detailed case analyses explored demographics, seizure types, neurological status, treatments, and quality of life.

Findings:

A significant association exists between epilepsy and obsessive-compulsive disorder (OCD).
Co-occurring epilepsy and OCD present unique challenges impacting patient well-being and treatment efficacy.

Implications:

Understanding the link between epilepsy and OCD is vital for comprehensive patient care.
Personalized treatment strategies are essential to effectively manage comorbid epilepsy and OCD, improving patient outcomes.