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Exploring new transcranial electrical stimulation strategies to modulate brain function in animal models
Carlos A Sánchez-León1, Álvaro Sánchez-López1, Claudia Ammann2
1Department of Physiology, Anatomy and Cell Biology, Pablo de Olavide University, 41013-Seville, Spain.
Current Opinion in Biomedical Engineering
|October 2, 2018
Summary
Animal models are crucial for understanding transcranial electrical stimulation (tES) effects, safety, and therapeutic potential in humans. Studies in animals advance tES protocols for improved brain stimulation and focality.
Area of Science:
- Neuroscience
- Biomedical Engineering
Background:
- Transcranial electrical stimulation (tES) encompasses non-invasive techniques modulating human cortical neuron excitability.
- Animal models are increasingly vital for elucidating tES mechanisms and applications.
Purpose of the Study:
- To highlight the essential role of animal models in advancing transcranial electrical stimulation research.
- To underscore the importance of animal studies for developing novel tES protocols and therapeutic strategies.
Main Methods:
- Review of studies utilizing animal models to investigate transcranial electrical stimulation.
- Analysis of how animal research informs safety limits and therapeutic potential of tES.
Main Results:
- Animal model studies are essential for disentangling neuromodulatory effects of tES.
- Research in animal models aids in defining safety parameters and exploring therapeutic uses for neurological disorders.
Conclusions:
- Knowledge from animal model studies is fundamental for the successful and controlled application of tES in humans.
- Animal research facilitates the development of advanced tES protocols, enhancing focality and deep-brain stimulation capabilities.
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