[АNALYSIS OF LETHALITY IN COMPLICATED DIABETIC FOOT SYNDROME AND SEPSIS].

Area of Science:

• Clinical Medicine
• Infectious Diseases
• Vascular Surgery

Background:

• Diabetic foot syndrome (DFS) is a severe complication of diabetes.
• Sepsis significantly increases morbidity and mortality in DFS patients.
• Wet gangrene of the lower extremities is a common cause of sepsis in DFS.

Purpose of the Study:

• To analyze the clinical characteristics and outcomes of patients with complicated diabetic foot syndrome.
• To investigate the impact of sepsis on DFS patient outcomes.
• To determine the effectiveness of surgical intervention in DFS management.

Main Methods:

• Dynamic examination of 724 patients with complicated diabetic foot syndrome.
• Analysis of disease severity, duration of purulent-necrotic process, and sepsis presence.
• Comparison of outcomes between operated and non-operated DFS patients.
• Identification of sepsis causes and mortality rates.

Main Results:

• Sepsis complicated DFS in 9.8% of patients (71 out of 724).
• Mortality was significantly higher in septic DFS patients (59.1%) compared to non-septic patients (5.5%).
• Wet gangrene was the predominant cause of sepsis in DFS.
• Non-operated septic patients had a 30.9% mortality rate, with 5 deaths occurring rapidly due to irreversible organ damage.

Conclusions:

• Sepsis is a critical factor influencing mortality in diabetic foot syndrome.
• Surgical intervention appears vital for DFS management, especially in non-septic cases.
• Prompt medical and surgical care is essential for improving survival rates in complicated DFS.