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Updated: Feb 4, 2026

Evaluation of Right Ventricular Function in Experimental Models of Pulmonary Arterial Hypertension
Published on: June 27, 2025
[RESULTS OF THE TOTAL CAVA-PULMONARY CONNECTION PROCEDURE WITH CORRECTION OF ATRIO-VENTRICULAR VALVES IN PATIENTS OF
Insights
This study improved management for single ventricle patients undergoing total cavopulmonary connection (TCPC) and atrioventricular valve (AVV) repair. A complex approach using multiple plasty procedures, including fiber ring stabilization, achieved optimal results in 92% of patients.
Area of Science:
- Cardiovascular Surgery
- Pediatric Cardiology
Background:
- Single ventricle physiology presents complex surgical challenges.
- Atrioventricular valve insufficiency is a common complication after total cavopulmonary connection (TCPC).
Purpose of the Study:
- To enhance patient management following TCPC with atrioventricular valve (AVV) insufficiency.
- To evaluate the outcomes of complex AVV repair strategies in single ventricle patients.
Main Methods:
- Analysis of immediate and middle-term results in 132 patients who underwent TCPC from 2005-2015.
- Focus on a subgroup of 24 patients with moderate to severe systemic AVV insufficiency.
- Application of multiple plasty procedures, including fiber ring stabilization, for AVV correction.
Main Results:
- Successful early and middle-term outcomes were achieved in 92% of the selected patient cohort.
- Multiple reconstructive procedures were necessary in 8 patients undergoing AVV correction.
- Complex surgical strategies, particularly fiber ring stabilization, correlated with optimal results.
Conclusions:
- A comprehensive surgical approach combining various plasty techniques is crucial for optimal AVV correction in TCPC patients.
- Fiber ring stabilization techniques significantly contribute to achieving superior outcomes in managing AVV insufficiency.
- Improved patient management strategies can lead to better long-term results for single ventricle physiology.
Abstract:
The investigation objective was to improve the patients’ management, suffering a single cardiac ventriculus, in whom a total cavа-pulmonary connection (ТСРС) operation was performed together with correction of the atrio-ventricular valves (AVV) insufficiency, basing on analysis of immediate and middle-term results. From 2005 to 2015 yrs in the clinic the ТСРС operation was performed in 132 patients. Of them 24 patients were choosed , in whom moderate and pronounced insufficiency of systemic AVV was diagnosed. Good early and middle-term results were achieved in 92% patients. In 8 observations, while the AVV correcting, in every patient two and more procedures of plasty were applied. Complex approach, using combination of various procedures of plasty, has guaranteed the optimal result. Application of procedures for the fiber ring stabilization have promoted achievement of best results.
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