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Updated: Feb 4, 2026

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Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy
Published on: August 22, 2025
817
[APPLICATION OF VACUUM-THERAPY IN COMPLEX OF TREATMENT OF THE LOWER EXTREMITIES CHRONIC WOUNDS]
Klinichna Khirurhiia
|October 2, 2018
Summary
This study analyzed chronic wound treatment using vacuum-assisted closure (VAC) therapy with a domestic device. Complex therapy, including VAC, autodermoplasty, and skin regeneration material, achieved significant healing in most patients.
Area of Science:
- Medicine
- Surgery
- Wound Healing
Background:
- Chronic wounds pose a significant clinical challenge, often requiring complex treatment strategies.
- Negative pressure wound therapy (NPWT) has emerged as a valuable modality for managing chronic wounds.
Purpose of the Study:
- To evaluate the efficacy of a comprehensive treatment approach for chronic wounds.
- To assess the impact of vacuum-assisted closure (VAC) therapy, using a specific domestic apparatus, as part of complex wound management.
Main Methods:
- Analysis of treatment experience in 11 patients with chronic wounds between 2014-2016.
- Application of vacuum-assisted closure (VAC) therapy with the "АGАТ- Dnepr" apparatus, both pre- and postoperatively.
- Integration of autodermoplasty, subcutaneous injection of "lacerta" skin regeneration material, and Ialuset-cream bandages into the treatment protocol.
Main Results:
- The average duration of stationary treatment was 38.3 days.
- Complete wound defect healing was achieved in 63% of patients within 1-5 weeks.
- An additional 26% of patients achieved complete healing within 6 weeks.
Conclusions:
- Complex treatment incorporating vacuum-assisted closure (VAC) therapy demonstrates high efficacy in managing chronic wounds.
- The "АGАТ- Dnepr" apparatus, used in conjunction with other therapeutic modalities, facilitates timely and complete wound closure.
- This integrated approach offers a promising strategy for improving outcomes in patients with chronic wounds.
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