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The Relation between Urinary Tract Infection and Febrile Seizure

Abolfazl Mahyar1, Parviz Ayazi1, Elaheh Azimi1

  • 1Qazvin Children Hospital, Qazvin University of Medical Sciences, Qazvin, Iran.

Iranian Journal of Child Neurology
|October 4, 2018
PubMed

Insights

Urinary tract infection (UTI) is a significant risk factor for febrile seizures in children. Promptly examining children with febrile seizures for UTI is crucial for effective management and prevention.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Neurology

Background:

  • Febrile seizure is the most common seizure type in children.
  • Identifying associated risk factors for febrile seizures is critical for clinical practice.

Purpose of the Study:

  • To investigate the association between urinary tract infection (UTI) and febrile seizures in children.
  • To determine if UTI is a risk factor for febrile seizures.

Main Methods:

  • A case-control study was conducted with 165 children diagnosed with simple febrile seizure (case group).
  • A control group of 165 children with fever but no seizure was included for comparison.
  • Urinary tract infection prevalence was assessed in both groups (children aged 6 months to 5 years).

Main Results:

  • Urinary tract infection was detected in 15.2% of children with febrile seizures, compared to only 1.2% in the control group (P=0.001).
  • Among children with febrile seizures and UTI, 68% had acute pyelonephritis and 32% had cystitis.
  • A significant association was found between UTI and febrile seizures.

Conclusions:

  • Urinary tract infection is identified as a potential risk factor for febrile seizures in children.
  • Routine screening for UTI is recommended for all children presenting with febrile seizures.
Abstract

Keywords:
ChildrenFebrile seizureUrinary tract infection

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