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Association between Gestational Weight Gain Adequacy and Adverse Maternal and Neonatal Outcomes
Han-Yang Chen1, Suneet P Chauhan1
1Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.
Insights
Excessive gestational weight gain (GWG) increases risks for maternal and neonatal morbidity. Inadequate GWG is linked to higher neonatal and infant mortality rates, highlighting the importance of appropriate GWG for better pregnancy outcomes.
Area of Science:
- Obstetrics and Gynecology
- Maternal-Fetal Medicine
- Public Health
Background:
- Gestational weight gain (GWG) recommendations aim to optimize maternal and infant health.
- Assessing GWG adequacy is crucial for identifying at-risk pregnancies.
- Previous studies have explored GWG but require stratification by prepregnancy BMI.
Purpose of the Study:
- To determine the prevalence of adequate GWG based on 2009 guidelines.
- To analyze the association between GWG adequacy and adverse maternal and neonatal outcomes.
- To stratify these associations by prepregnancy body mass index (BMI).
Main Methods:
- Retrospective cohort study utilizing U.S. linked birth/infant death datasets (2011-2013).
- Included nonanomalous singleton live births (37-41 weeks gestation).
- Multivariable Poisson regression models assessed associations between GWG adequacy and composite maternal morbidity (CMM), composite neonatal morbidity (CNM), and mortality.
Main Results:
- Prevalence: 20% inadequate GWG, 32% adequate GWG, 48% excessive GWG.
- Excessive GWG correlated with increased risk of CMM (1.10) and CNM (1.12).
- Inadequate GWG correlated with increased risk of neonatal mortality (1.14) and infant mortality (1.12).
Conclusions:
- Excessive GWG is linked to higher risks of maternal and neonatal morbidity.
- Inadequate GWG is associated with increased neonatal and infant mortality.
- GWG adequacy is a significant factor influencing adverse pregnancy outcomes across BMI categories.
Objectives:
To estimate the prevalence of gestational weight gain (GWG) adequacy according to the 2009 guidelines, and to examine the association between GWG adequacy and the adverse outcomes, stratified by prepregnancy body mass index (BMI).
Study Design:
A retrospective cohort study, using the 2011 to 2013 U.S. linked birth/infant death datasets, restricted to nonanomalous singleton live births at 37 to 41 weeks. The adverse outcomes included composite maternal morbidity (CMM), composite neonatal morbidity (CNM), and neonatal and infant mortalities. We used multivariable Poisson's regression models with robust error variance to examine the association between GWG adequacy and adverse outcomes.
Results:
Of 8,656,791 singleton live births, 20, 32, and 48% had inadequate, adequate, and excessive GWG, respectively. After multivariable regression adjustment, compared with adequate GWG, excessive GWG had 1.10 (1.08-1.13) and 1.12 (1.10-1.14) times higher risk of CMM and CNM, respectively; similar findings were observed in BMI subgroups. Compared with adequate GWG, inadequate GWG had 1.14 (1.03-1.26) and 1.12 (1.07-1.18) times higher risk of neonatal and infant mortalities, respectively. Similar results were noted among women with normal weight.
Conclusion:
Excessive GWG was associated with an increased risk of CMM and CNM, while inadequate GWG was associated with a higher risk of neonatal and infant mortalities.
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